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- Title
胸部 CT 联合血清糖类抗原 -125、降钙素原、 酌- 干扰素诱导蛋白 10 对肺结核的诊断价值.
- Authors
王 磊; 来守勇; 林 荫; 郭 玲; 高 孟
- Abstract
Objective: To investigate the diagnostic value of chest computed tomography (CT) combined with serum carbohydrate antigen-125(CA125), procalcitonin (PCT) and interferon-γ-inducible protein 10(IP10) in pulmonary tuberculosis. Methods: 108 patients with suspected pulmonary tuberculosis who were admitted to our hospital from January 2020 to January 2022 were selected, and they were divided into pulmonary tuberculosis group(71 cases) and non-pulmonary tuberculosis group(37 cases) according to biopsy results. All patients underwent chest CT examination, the levels of serum CA125, PCT and IP-10 were detected. Receiver operating characteristic (ROC) curve was used to analyze the diagnostic value of chest CT combined with serum CA125, PCT and IP-10 for pulmonary tuberculosis. Results: Among the 108 cases of patients with suspected tuberculosis, 71 cases were confirmed, with a detection rate of 65.74%. The chest CT findings of patients with pulmonary tuberculosis were large consolidation shadows or scattered multiple spots, accompanied by cavity, tree bud sign or pleural effusion, pleural thickening and nodular lesions. The levels of serum CA125, PCT and IP-10 in the pulmonary tuberculosis group were higher than those in the non-pulmonary tuberculosis group(P<0.05). The area under curve of chest CT, CA125, PCT and IP-10 for the diagnosis of pulmonary tuberculosis was 0.759, 0.715, 0.688 and 0.727, respectively, the area under curve of chest CT, CA125, PCT and IP-10 for the diagnosis of pulmonary tuberculosis was 0.876, which was higher than chest CT, CA125, PCT, IP-10 alone diagnosis. Conclusions: Chest CT can show the typical lesion characteristics of pulmonary tuberculosis, and the levels of serum CA125, PCT and IP-10 in patients with pulmonary tuberculosis are significantly increased. The combination of chest CT, CA125, PCT and IP-10 can improve the diagnostic efficiency of pulmonary tuberculosis.
- Subjects
TUBERCULOSIS; COMPUTED tomography; RECEIVER operating characteristic curves; MULTIPLE scattering (Physics); CHEST examination; PLEURA diseases
- Publication
Progress in Modern Biomedicine, 2023, Vol 23, Issue 12, p2291
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2023.12.016