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- Title
Intracranial Internal Carotid Artery Calcification: A Representative for Cerebral Artery Calcification and Association with White Matter Hyperintensities.
- Authors
Pil-Wook Chung; Kwang-Yeol Park; Heui-Soo Moon; Yong-Bum Kim; Young Chul Youn; Jun Soo Byun; Oh-Sang Kwon
- Abstract
Background: Our aim was to investigate the distribution pattern of cerebral artery calcification and its association with white matter hyperintensities (WMH). Methods: We identified 159 consecutive patients with acute ischemic stroke. Calcifications of cerebral arteries and WMH were graded. Results: Cerebral artery calcification was found in 137 patients (86.2%). The intracranial internal carotid artery (I-ICA) was the most frequently affected artery with calcification (76.7%) and moderate-to-severe calcification (38.1%). Spearman’s rank test revealed that the grade of I-ICA calcification was correlated with those of periventricular WMH (r = 0.417, p < 0.001) and deep WMH (r = 0.388, p < 0.001). The adjusted ORs of I-ICA were 2.62 (p <0.05) for periventricular WMH and 3.25 (p <0.05) for deep WMH. Conclusions: Cerebral artery calcification is common in patients with ischemic stroke. I-ICA is the most frequently and most severely affected cerebral artery and its calcification is associated with WMH. Copyright © 2010 S. Karger AG, Basel
- Subjects
CALCIFICATION; CAROTID artery diseases; CEREBRAL arterial diseases; ISCHEMIA; CEREBROVASCULAR disease patients
- Publication
Cerebrovascular Diseases, 2010, Vol 30, Issue 1, p65
- ISSN
1015-9770
- Publication type
Article
- DOI
10.1159/000314622