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- Title
Daratumumab as rescue therapy in life-threatening granulomatosis with polyangiitis.
- Authors
Krusche, Martin; Oqueka, Tim; Wichmann, Dominic; Kluge, Stefan; Huber, Tobias B; Kötter, Ina; Schmidt-Lauber, Christian
- Abstract
The article describes a case of a female patient with severe granulomatosis with polyangiitis. Topics mentioned include the management of the patient with daratumumab, the clinical features of the autoimmune serology, the key symptoms of the disease, the effect of rituximab, and the use of extracorporeal membrane oxygenation therapy.
- Subjects
THERAPEUTIC use of monoclonal antibodies; THERAPEUTICS; AUTOANTIBODIES; GLUCOCORTICOIDS; BIOPSY; INFLAMMATION; RENAL replacement therapy; EXTRACORPOREAL membrane oxygenation; MULTIPLE organ failure; GRANULOMATOSIS with polyangiitis; CATASTROPHIC illness; TREATMENT effectiveness; COUGH; FATIGUE (Physiology); COMPUTED tomography; IMMUNOSUPPRESSIVE agents; PREDNISONE; EARACHE; ACUTE kidney failure; DISEASE complications
- Publication
Rheumatology, 2024, Vol 63, Issue 3, pe94
- ISSN
1462-0324
- Publication type
Article
- DOI
10.1093/rheumatology/kead474