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- Title
patient with acute-onset hemorrhagic necroses and bullae of the legs.
- Authors
Graßhoff, Hanna; Sailer, Verena-Wilbeth; Humrich, Jens; Riemekasten, Gabriela; Lamprecht, Peter
- Abstract
The article describes the case of a 30-year-old woman with sudden onset of large irregular shaped confluent hemorrhagic necrosis, ecchymoses and bullae affecting both legs. Topics discussed include findings on laboratory evaluation, diagnosis of systemic lupus erythematosus (SLE) and Sanarelli Shwartzman phenomenon, and disseminated microthrombi in cutaneous vessels without signs of vasculitis revealed in dermal biospy.
- Subjects
SYSTEMIC lupus erythematosus diagnosis; THERAPEUTIC use of glucocorticoids; LEG surgery; VASCULAR disease diagnosis; DISSEMINATED intravascular coagulation; PHYSICAL diagnosis; C-reactive protein; PROTHROMBIN time; RITUXIMAB; BIOPSY; DEBRIDEMENT; SKIN grafting; HEMOSTASIS; MYCOPHENOLIC acid; LEG; BLISTERS; CYCLOSPORINE; BLOOD coagulation disorders; CYCLOPHOSPHAMIDE; SYSTEMIC lupus erythematosus; VASCULAR diseases; ECCHYMOSIS; THROMBOCYTOPENIA; INTERNATIONAL normalized ratio; HYDROXYCHLOROQUINE; HEMORRHAGE; NECROSIS; FIBRIN fibrinogen degradation products; SYMPTOMS; THERAPEUTICS; ADULTS
- Publication
Rheumatology, 2021, Vol 60, Issue 11, p5476
- ISSN
1462-0324
- Publication type
Case Study
- DOI
10.1093/rheumatology/keab399