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- Title
Successful Treatment of Infantile Fibrosarcoma Spinal Metastasis by Chemotherapy and Stereotactic Hypofractionated Radiotherapy.
- Authors
Cheng-Hsiang Lo; Shin-Nan Cheng; Kuen-Tze Lin; Yee-Min Jen
- Abstract
We report a case of infantile fibrosarcoma in an 8-month-old boy manifested as a right-sided lower leg mass. Repeated local recurrence and distant metastasis were noted during the following three-year period. Whole body fluoro-deoxyglucose positron emission tomography scan revealed an asymptomatic metastasis involving the fourth lumbar vertebrae. The patient received chemotherapy (VAC regimen) with Cyberknife® stereotactic hypofractionated radiotherapy (26 Gy; 4 fractions). This treatment reduced tumor size by 23% without acute radiation toxicity even after 33 months. This case suggests that combining chemotherapy and this form of radiotherapy may be safe and effective against childhood spinal metastasis.
- Subjects
FIBROSARCOMA; CANCER invasiveness; CANCER relapse; METASTASIS; POSITRON emission tomography; LUMBAR vertebrae
- Publication
Journal of Korean Neurosurgical Society, 2013, Vol 54, Issue 6, p528
- ISSN
2005-3711
- Publication type
Case Study
- DOI
10.3340/jkns.2013.54.6.528