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- Title
DETERMINATION OF BIOLOGICAL ACTIVITY, ANTIOXIDANT ACTIVITY AND SYNTHESIS OF TRIAZOLOPYRIMIDINES.
- Authors
Gilava, V. P.; Patel, P. K.; Ram, H. K.; Chauhan, J. H.
- Abstract
Potent Synthesis of an uncommon series of 7-(4-(benzyloxy)-3-methoxyphenyl)-N-(4- chlorophenyl)-4,7-dihydro-5- methyl-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide (V1-V10)was accomplished using Biginelli protocol from 4-(benzyloxy)-3-methoxybenzaldehyde, N-(substituted phenyl)-3-oxobutanamide and 2H-1,2,4-triazol-3-amine and few drop of N,N-Dimethylformamide. All the synthesized compounds were characterized by IR, NMR, mass spectroscopic techniques and elemental analyses. All the synthesized compounds were evaluated for their antimicrobial activity and antioxidant activity.
- Subjects
CHEMICAL synthesis; ANTIOXIDANTS
- Publication
Rasayan Journal of Chemistry, 2020, Vol 13, Issue 4, p2249
- ISSN
0974-1496
- Publication type
Article
- DOI
10.31788/RJC.2020.1346072