We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Immobilized Eosin Y for the Photocatalytic Oxidation of Tetrahydroisoquinolines in Flow.
- Authors
Herbrik, Fabian; Rossi, Sergio; Sanz, Miguel; Puglisi, Alessandra; Benaglia, Maurizio
- Abstract
A new easy‐to‐synthesize solid supported Eosin Y and its application in the building of a catalytic continuous flow reactor is reported. The fluidic device was employed to perform tertiary amines in‐flow photooxidations followed by a nucleophile addition, with overall productivity increased by one order magnitude. When using the iminium‐ions in situ generated or in a telescoped fashion, the resulting Mannich‐products were isolated with high diastereoselectivity and up to 90 % enantioselectivity, simply using air as terminal oxidant.
- Subjects
PHOTOCATALYTIC oxidation; CONTINUOUS flow reactors; TETRAHYDROISOQUINOLINES; FLUIDIC devices; EOSIN
- Publication
ChemCatChem, 2022, Vol 14, Issue 17, p1
- ISSN
1867-3880
- Publication type
Article
- DOI
10.1002/cctc.202200461