We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Efficacy and safety of subcutaneous immunotherapy for inhalable allergens in patients with respiratory allergy after one year of treatment.
- Authors
Sánchez-Villalobos, Johav Yael; Caballero-López, Chrystopherson; López-García, Aída Inés; Rivero-Yeverino, Daniela; Arana-Muñoz, Oswaldo; Papaqui-Tapia, José Sergio; Ríos-López, Juan Jesús; Payán-Díaz, Jonathan Higgins; López-Romero, Carlos David; Villada-Villada, Erika
- Abstract
Background: Allergen-specific immunotherapy is an important therapeutic alternative for the management of allergic rhinitis and asthma. Objective: To evaluate the efficacy and safety of subcutaneous immunotherapy with allergens in patients with respiratory allergy at the University Hospital of Puebla after twelve months of treatment. Methods: Longitudinal, sequential, analytical, quasi-experimental, prolective study. For twelve months we included patients with asthma and/or rhinitis, sensitized to aeroallergens, aged 4 to 65 years and of both genders. The CARAT and Portnoy questionnaires were collected every two months to assess efficacy and safety, respectively. Results: 47 patients were included, 37 (78.7 %) women. The average age was 29.8 years. 76.6 % had a diagnosis of allergic rhinitis and 23.4 % of asthma and allergic rhinitis. When comparing the average score of the initial CARAT against the final average by means of a t test, a t value of -8.86 and a p < 0.05 were obtained. It was obtained a total frequency of local adverse reactions of 19 % and systemic adverse reactions of 2.1 % at 6 and 12 months of treatment. Conclusions: The immunotherapy scheme evaluated, derived from the Mexican clinical practice guidelines of immunotherapy 2011, is effective with a convenient safety profile.
- Subjects
IMMUNOTHERAPY; ALLERGENS; HAY fever treatment; ASTHMA treatment; RESPIRATORY allergy; DRUG efficacy
- Publication
Revista Alergia de Mexico, 2020, Vol 67, Issue 4, p309
- ISSN
0002-5151
- Publication type
Article
- DOI
10.29262/ram.v67i4.758