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- Title
Human coronavirus OC43 causes influenza-like illness in residents and staff of aged-care facilities in Melbourne, Australia.
- Authors
Birch CJ; Clothier HJ; Seccull A; Tran T; Catton MC; Lambert SB; Druce JD; Birch, C J; Clothier, H J; Seccull, A; Tran, T; Catton, M C; Lambert, S B; Druce, J D
- Abstract
Three outbreaks of respiratory illness associated with human coronavirus HCoV-OC43 infection occurred in geographically unrelated aged-care facilities in Melbourne, Australia during August and September 2002. On clinical and epidemiological grounds the outbreaks were first thought to be caused by influenza virus. HCoV-OC43 was detected by RT-PCR in 16 out of 27 (59%) specimens and was the only virus detected at the time of sampling. Common clinical manifestations were cough (74%), rhinorrhoea (59%) and sore throat (53%). Attack rates and symptoms were similar in residents and staff across the facilities. HCoV-OC43 was also detected in surveillance and diagnostic respiratory samples in the same months. These outbreaks establish this virus as a cause of morbidity in aged-care facilities and add to increasing evidence of the significance of coronavirus infections.
- Publication
Epidemiology & Infection, 2005, Vol 133, Issue 2, p273
- ISSN
0950-2688
- Publication type
journal article
- DOI
10.1017/s0950268804003346