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- Title
Characterization of the aminated agarose nanoparticles labeled with fluorescein isothiocyanate.
- Authors
Zhang, Ling-Min; Huang, Jian-Yan; Zhang, Ling-Hui; Chu, Bin; Tang, Shun-Qing
- Abstract
Incorporating an organic fluorescence agent into nanoparticles can significantly promote its fluorescent efficiency. In this article, a novel fluorescein isothiocyanate labeling aminated agarose (FITC-AA) was synthesized and tested as an effective fluorescent labeling agent. FITC-AA could spontaneously form nanoparticles with a diameter less than 200 nm below 37°C due to gelling effect of the agarose. Cell culture experiments confirmed that 3T3 fibroblast cells could be marked by fluorescent FITC-AA nanoparticles and the labeling time sustained longer than by FITC alone. This finding demonstrates that the fluorescent labeling of cells can be enhanced when fluorescent nanoparticles are used as markers. SCANNING 32: 361-368, 2010. © 2010 Wiley Periodicals, Inc.
- Publication
Scanning, 2010, Vol 32, Issue 6, p361
- ISSN
0161-0457
- Publication type
Article
- DOI
10.1002/sca.20205