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- Title
Minimum clinical important difference for resilience scale specific to cancer: a prospective analysis.
- Authors
Ye, Zeng Jie; Zhang, Zhang; Tang, Ying; Liang, Jian; Zhang, Xiao Ying; Hu, Guang Yun; Sun, Zhe; Liang, Mu Zi; Yu, Yuan Liang
- Abstract
<bold>Background: </bold>The minimum clinical important differences (MCIDs) of resilience instruments in patients with cancer have not been comprehensively described. This study was designed to evaluate MCIDs of 10-item and 25-item resilience scales specific to cancer (RS-SC-10 and RS-SC-25).<bold>Methods: </bold>From June 2015 to December 2018, RS-SCs were longitudinally measured in 765 patients with different cancer diagnoses at baseline (T0) and 3 months later (T1). The EORTC QLQ-C30, Connor-Davidson Resilience Scale, Hospital Anxiety and Depression Scale, and Allostatic Load Index were measured concurrently as anchors. Anchor-based methods (linear regression, within-group), distribution-based methods(within-group), and receiver operating characteristic curves (ROCs, within-subject) were performed to evaluate the MCIDs.<bold>Results: </bold>623 of 765 (84.1%) patients had paired RS-SCs scores. Moderate correlations were identified between the change in RS-SCs and change in anchors (r = 0.38-0.44, all p < 0.001). Linear regression estimated + 8.9 and - 6.7 as the MCIDs of RS-SC-25, and + 3.4 and - 2.5 for RS-SC-10. Distribution-based methods estimated + 9.9 and - 9.9 as the MCIDs of RS-SC-25, and + 4.0 and - 4.0 for RS-SC-10. ROC estimated + 5.5 and - 4.5 as the MCIDs of RS-SC-25, and + 2.0 and - 1.5 for RS-SC-10.<bold>Conclusions: </bold>The most reliable MCID is around 5 points for RS-SC-25 and 2 points for RS-SC-10. RS-SCs are more responsive to the worsening status of resilience in patients with cancer and these estimates could be useful in future resilience-based intervention trials.
- Subjects
PSYCHOLOGICAL resilience; RECEIVER operating characteristic curves; EXPERIMENTAL design
- Publication
Health & Quality of Life Outcomes, 2020, Vol 18, Issue 1, p1
- ISSN
1477-7525
- Publication type
journal article
- DOI
10.1186/s12955-020-01631-6