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- Title
Recurrences after Local Excision for Early Rectal Adenocarcinoma.
- Authors
Jung Wook Huh; Park, Yoon Ah; Kang Young Lee; Seong Ah Kim; Seung-Kook Sohn
- Abstract
Purpose: The role of local excision in treating rectal cancer patients continues to be controversial. The aim of this study was to evaluate the long-term oncological results of local excision for early rectal adenocarcinomas and review the outcomes of salvage therapy on rectal cancer patients. Materials and Methods: Between March 1992 and September 2005, 35 consecutive patients with early-stage primary rectal adenocarcinomas were treated by local excision with curative intent. The mean tumor distance from the anal verge was 5 cm (range, 1-10 cm). Results: The median follow-up was 66 months (range, 17-161 months). Pathological examination revealed 23 cases of T1 and 12 cases of T2. Recurrence had developed in 10 patients (6 local recurrences, 4 systemic recurrences). Purely extrapelvic recurrence was observed in only two (5.7%) patients. Of the eight recurrent patients with surgical salvage, five survived with no evidence of disease at the time of this analysis. The 5-year local recurrence-free and disease-free survival rates were 79.6% and 67.9%, respectively. Conclusion: Local excision alone of early-staged rectal adenocarcinomas, even in the ideal candidate, is followed by a relatively higher local recurrence rate than previously reported and may not be a valid modality. Either the use of adjuvant therapy with local excision, even in patients with T1 lesions or the use of preoperative therapy followed by local excision has good promise.
- Subjects
CANCER relapse; RECTAL cancer; RECTAL surgery; SALVAGE therapy; CANCER treatment; CANCER patients; OPERATIVE surgery
- Publication
Yonsei Medical Journal, 2009, Vol 50, Issue 5, p704
- ISSN
0513-5796
- Publication type
Article
- DOI
10.3349/ymj.2009.50.5.704