We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A Facile Synthesis of Aryl-Substituted Hydrazono-Pyrazolyl[1,2,4]triazolo[3,4- b][1,3,4][thiadiazol]-coumarin Derivatives.
- Authors
Sharma, Archi; Satish, Gudala; Penta, Santhosh
- Abstract
Some inimitable and therapeutic coumarin-substituted fused[1,2,4]triazolo-[3,4- b][1,3,4]thiadizole derivatives were synthesized by the reaction of 2-oxo-2 H-chromene-3-carboxylic acid ( 1) and 4-amino-5-hydrazinyl-4 H-[1,2,4]-triazole-3-thiol ( 2) by using phosphorous oxychloride as a cyclizing agent. This cyclized 3-(3-hydrazino-[1,2,4]triazolo[3,4- b][1,3,4]thiadiazol-6-yl)-chromen-2-one ( 3) later condensation with various ethyl 2-(2-arylhydrazono)-3-oxobutanoates ( 4) in NaOAc/MeOH under reflux conditions afforded the corresponding new series of aryl-substituted hydrazono-pyrazolyl-[1,2,4]triazolo[3,4- b][1,3,4][thiadiazol]-coumarin derivatives ( 5) in good to excellent yields. The structures of newly synthesized compounds were established on the basis of elemental analysis, IR, 1H NMR and mass spectroscopic studies.
- Subjects
PYRAZOLYL compounds; CARBOXYLIC acids; CHEMICAL synthesis; COUMARINS; THIADIAZOLES
- Publication
Journal of Heterocyclic Chemistry, 2016, Vol 53, Issue 4, p1086
- ISSN
0022-152X
- Publication type
Article
- DOI
10.1002/jhet.2362