We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
P wave dispersion in obese dogs with and without mitral valve disease.
- Authors
Dittrich, Gustavo; Van Der Broocke Campos, Gabriela Marin; Gonçalves Sousa, Marlos; Tostes Oliveira, Simone
- Abstract
Pwave dispersion (Pd) is an electrocardiographic index defined as the difference between the minimum and maximum Pwave duration in multiple leads. The augmentation of Pd reflects the discontinuous and inhomogeneous atrial depolarization resulting from cardiac and non-cardiac conditions. In humans, an increased Pd is associated with the development of cardiac arrhythmias, particularly atrial fibrillation. To investigate Pd in obese dogs, we enrolled 76 dogs, which were classified in four distinct categories according to body condition and the existance of valve insufficiency: obese dogs (O), dogs with both obesity and cardiac disease (O+CD), lean dogs with cardiac disease (CD) and healthy controls (H). To be included in the study, all dogs underwent an electrocardiographic and echocardiographic assessment. We reported significantly higher Pd in the animals included in categories O, O+CD and CD (18.0±7.6ms, 16.1±4.4ms, 12.1±4.3ms, respectively) as compared to the healthy subjects (7.3±2.2ms). Also, significant correlations between Pd and both the body mass index and body fat percentage were documented for the obese dogs. However, no association between Pd and LA/Ao could be identified in patients belonging to the O, O+CD and H categories. Thus, we have demonstrated that obese dogs, regardless of their valvular competency status, present high Pd values, suggesting an impaired propagation of atrial electrical impulse.
- Subjects
OBESITY in animals; MITRAL valve diseases; DIAGNOSIS of dog diseases; ELECTROCARDIOGRAPHY; ARRHYTHMIA diagnosis; ATRIAL fibrillation; HEART diseases
- Publication
Ciência Rural, 2018, Vol 48, Issue 10, p1
- ISSN
0103-8478
- Publication type
Article
- DOI
10.1590/0103-8478cr20180047