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PFASs May Risk Alzheimer's Disease.
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2024, v. 79, n. 3, p. 1, doi. 10.1093/gerona/glad277
By:
- Wang, He-Ling;
- Fang, Evandro F
Publication type:
Article
Alzheimer's disease diagnostic accuracy by fluid and neuroimaging ATN framework.
Published in:
CNS Neuroscience & Therapeutics, 2024, v. 30, n. 2, p. 1, doi. 10.1111/cns.14357
By:
- Xiong, Xi;
- He, Haijun;
- Ye, Qianqian;
- Qian, Shuangjie;
- Zhou, Shuoting;
- Feng, Feifei;
- Fang, Evandro F.;
- Xie, Chenglong
Publication type:
Article
Amyloid-β toxicity modulates tau phosphorylation through the PAX6 signalling pathway.
Published in:
2021
By:
- Zhang, Yalun;
- Zhang, Yi;
- Aman, Yahyah;
- Ng, Cheung Toa;
- Chau, Wing-Hin;
- Zhang, Zhigang;
- Yue, Ming;
- Bohm, Christopher;
- Jia, Yizhen;
- Li, Siwen;
- Yuan, Qiuju;
- Griffin, Jennifer;
- Chiu, Kin;
- Wong, Dana S M;
- Wang, Binbin;
- Jin, Dongyan;
- Rogaeva, Ekaterina;
- Fraser, Paul E;
- Fang, Evandro F;
- George-Hyslop, Peter St
Publication type:
journal article
Urolithin A improves Alzheimer's disease cognition and restores mitophagy and lysosomal functions.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 6, p. 4212, doi. 10.1002/alz.13847
By:
- Hou, Yujun;
- Chu, Xixia;
- Park, Jae‐Hyeon;
- Zhu, Qing;
- Hussain, Mansoor;
- Li, Zhiquan;
- Madsen, Helena Borland;
- Yang, Beimeng;
- Wei, Yong;
- Wang, Yue;
- Fang, Evandro F.;
- Croteau, Deborah L.;
- Bohr, Vilhelm A.
Publication type:
Article
DNA Damage-Induced Neurodegeneration in Accelerated Ageing and Alzheimer's Disease.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 13, p. 6748, doi. 10.3390/ijms22136748
By:
- Wang, Heling;
- Lautrup, Sofie;
- Caponio, Domenica;
- Zhang, Jianying;
- Fang, Evandro F.
Publication type:
Article
GAK and PRKCD are positive regulators of PRKN-independent mitophagy.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26331-7
By:
- Munson, Michael J.;
- Mathai, Benan J.;
- Ng, Matthew Yoke Wui;
- Trachsel-Moncho, Laura;
- de la Ballina, Laura R.;
- Schultz, Sebastian W.;
- Aman, Yahyah;
- Lystad, Alf H.;
- Singh, Sakshi;
- Singh, Sachin;
- Wesche, Jørgen;
- Fang, Evandro F.;
- Simonsen, Anne
Publication type:
Article
Studying Werner syndrome to elucidate mechanisms and therapeutics of human aging and age-related diseases.
Published in:
Biogerontology, 2019, v. 20, n. 3, p. 255, doi. 10.1007/s10522-019-09798-2
By:
- Lautrup, Sofie;
- Caponio, Domenica;
- Cheung, Hoi-Hung;
- Piccoli, Claudia;
- Stevnsner, Tinna;
- Chan, Wai-Yee;
- Fang, Evandro F.
Publication type:
Article
Proteins with antifungal properties and other medicinal applications from plants and mushrooms.
Published in:
Applied Microbiology & Biotechnology, 2010, v. 87, n. 4, p. 1221, doi. 10.1007/s00253-010-2690-4
By:
- Wong, Jack H.;
- Ng, T. B.;
- Cheung, Randy C. F.;
- Ye, X. J.;
- Wang, H. X.;
- Lam, S. K.;
- Lin, P.;
- Chan, Y. S.;
- Fang, Evandro F.;
- Ngai, Patrick H. K.;
- Xia, L. X.;
- Jiang, Y.;
- Liu, F.
Publication type:
Article
Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway.
Published in:
Scientific Reports, 2017, p. 46208, doi. 10.1038/srep46208
By:
- Fang, Evandro F.;
- Waltz, Tyler B.;
- Kassahun, Henok;
- Lu, Qiping;
- Kerr, Jesse S.;
- Morevati, Marya;
- Fivenson, Elayne M.;
- Wollman, Bradley N.;
- Marosi, Krisztina;
- Wilson, Mark A.;
- Iser, Wendy B.;
- Eckley, D. Mark;
- Zhang, Yongqing;
- Lehrmann, Elin;
- Goldberg, Ilya G.;
- Scheibye-Knudsen, Morten;
- Mattson, Mark P.;
- Nilsen, Hilde;
- Bohr, Vilhelm A.;
- Becker, Kevin G.
Publication type:
Article
Iron out, mitophagy in! A way to slow down hepatocellular carcinoma.
Published in:
EMBO Reports, 2020, v. 21, n. 11, p. 1, doi. 10.15252/embr.202051652
By:
- Aman, Yahyah;
- Cao, Shuqin;
- Fang, Evandro F.
Publication type:
Article
NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-13172-8
By:
- Fang, Evandro F.;
- Hou, Yujun;
- Lautrup, Sofie;
- Jensen, Martin Borch;
- Yang, Beimeng;
- SenGupta, Tanima;
- Caponio, Domenica;
- Khezri, Rojyar;
- Demarest, Tyler G.;
- Aman, Yahyah;
- Figueroa, David;
- Morevati, Marya;
- Lee, Ho-Joon;
- Kato, Hisaya;
- Kassahun, Henok;
- Lee, Jong-Hyuk;
- Filippelli, Deborah;
- Okur, Mustafa Nazir;
- Mangerich, Aswin;
- Croteau, Deborah L.
Publication type:
Article
Targeting on the NAD+‐mitophagy axis to treat cardiovascular disease.
Published in:
Aging Medicine, 2020, v. 3, n. 3, p. 151, doi. 10.1002/agm2.12123
By:
- Fang, Evandro F.;
- Tao, Jun
Publication type:
Article
Boosting NAD ameliorates hematopoietic impairment linked to short telomeres in vivo.
Published in:
GeroScience, 2023, v. 45, n. 4, p. 2213, doi. 10.1007/s11357-023-00752-2
By:
- Stock, Amanda J.;
- Ayyar, Saipriya;
- Kashyap, Amogh;
- Wang, Yunong;
- Yanai, Hagai;
- Starost, Matthew F.;
- Tanaka-Yano, Mayuri;
- Bodogai, Monica;
- Sun, Chongkui;
- Wang, Yajun;
- Gong, Yi;
- Puligilla, Chandrakala;
- Fang, Evandro F.;
- Bohr, Vilhelm A.;
- Liu, Yie;
- Beerman, Isabel
Publication type:
Article
Long‐Term Nicotinamide Riboside Use Improves Coordination and Eye Movements in Ataxia Telangiectasia.
Published in:
Movement Disorders, 2024, v. 39, n. 2, p. 360, doi. 10.1002/mds.29645
By:
- Presterud, Rebecca;
- Deng, Wei Hai;
- Wennerström, Anna Berit;
- Burgers, Trudy;
- Gajera, Bharat;
- Mattsson, Kirsten;
- Solberg, Agnes;
- Fang, Evandro F.;
- Nieminen, Anni I.;
- Stray‐Pedersen, Asbjørg;
- Nilsen, Hilde
Publication type:
Article
TNF-α-dependent neuronal necroptosis regulated in Alzheimer's disease by coordination of RIPK1-p62 complex with autophagic UVRAG.
Published in:
Theranostics, 2021, v. 11, n. 19, p. 9452, doi. 10.7150/thno.62376
By:
- Chong Xu;
- Jialin Wu;
- Yiqun Wu;
- Zhichu Ren;
- Yuyuan Yao;
- Guobing Chen;
- Fang, Evandro F.;
- Ji Heon Noh;
- Liu, Yong U.;
- Libin Wei;
- Xijing Chen;
- Sima, Jian
Publication type:
Article
Turning up the NAD+-mitophagy axis to treat Alzheimer's disease.
Published in:
Neural Regeneration Research, 2023, v. 18, n. 2, p. 319, doi. 10.4103/1673-5374.346472
By:
- Fang, Evandro F.;
- Anisimov, Alexander
Publication type:
Article
P. edulis Extract Protects Against Amyloid-β Toxicity in Alzheimer's Disease Models Through Maintenance of Mitochondrial Homeostasis via the FOXO3/DAF-16 Pathway.
Published in:
Molecular Neurobiology, 2022, v. 59, n. 9, p. 5612, doi. 10.1007/s12035-022-02904-5
By:
- Cao, Shu-qin;
- Aman, Yahyah;
- Fang, Evandro F.;
- Tencomnao, Tewin
Publication type:
Article
Crosstalk among DNA Damage, Mitochondrial Dysfunction, Impaired Mitophagy, Stem Cell Attrition, and Senescence in the Accelerated Ageing Disorder Werner Syndrome.
Published in:
Cytogenetic & Genome Research, 2021, v. 161, n. 6/7, p. 297, doi. 10.1159/000516386
By:
- Gudmundsrud, Ruben;
- Skjånes, Tarjei H.;
- Gilmour, Brian C.;
- Caponio, Domenica;
- Lautrup, Sofie;
- Fang, Evandro F.
Publication type:
Article
A comprehensive AI‐driven analysis of large‐scale omic datasets reveals novel dual‐purpose targets for the treatment of cancer and aging.
Published in:
Aging Cell, 2023, v. 22, n. 12, p. 1, doi. 10.1111/acel.14017
By:
- Pun, Frank W.;
- Leung, Geoffrey Ho Duen;
- Leung, Hoi Wing;
- Rice, Jared;
- Schmauck‐Medina, Tomas;
- Lautrup, Sofie;
- Long, Xi;
- Liu, Bonnie Hei Man;
- Wong, Chun Wai;
- Ozerov, Ivan V.;
- Aliper, Alex;
- Ren, Feng;
- Rosenberg, Ari J.;
- Agrawal, Nishant;
- Izumchenko, Evgeny;
- Fang, Evandro F.;
- Zhavoronkov, Alex
Publication type:
Article
Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD+ signaling.
Published in:
Aging Cell, 2020, v. 19, n. 12, p. 1, doi. 10.1111/acel.13268
By:
- Okur, Mustafa N.;
- Fang, Evandro F.;
- Fivenson, Elayne M.;
- Tiwari, Vinod;
- Croteau, Deborah L.;
- Bohr, Vilhelm A.
Publication type:
Article
DNA polymerase β decrement triggers death of olfactory bulb cells and impairs olfaction in a mouse model of Alzheimer's disease.
Published in:
Aging Cell, 2017, v. 16, n. 1, p. 162, doi. 10.1111/acel.12541
By:
- Misiak, Magdalena;
- Vergara Greeno, Rebeca;
- Baptiste, Beverly A.;
- Sykora, Peter;
- Liu, Dong;
- Cordonnier, Stephanie;
- Fang, Evandro F.;
- Croteau, Deborah L.;
- Mattson, Mark P.;
- Bohr, Vilhelm A.
Publication type:
Article

Found: 21

PFASs May Risk Alzheimer's Disease.

Alzheimer's disease diagnostic accuracy by fluid and neuroimaging ATN framework.

Amyloid-β toxicity modulates tau phosphorylation through the PAX6 signalling pathway.

Urolithin A improves Alzheimer's disease cognition and restores mitophagy and lysosomal functions.

DNA Damage-Induced Neurodegeneration in Accelerated Ageing and Alzheimer's Disease.

GAK and PRKCD are positive regulators of PRKN-independent mitophagy.

Studying Werner syndrome to elucidate mechanisms and therapeutics of human aging and age-related diseases.

Proteins with antifungal properties and other medicinal applications from plants and mushrooms.

Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway.

Iron out, mitophagy in! A way to slow down hepatocellular carcinoma.

NAD<sup>+</sup> augmentation restores mitophagy and limits accelerated aging in Werner syndrome.

Targeting on the NAD<sup>+</sup>‐mitophagy axis to treat cardiovascular disease.

Boosting NAD ameliorates hematopoietic impairment linked to short telomeres in vivo.

Long‐Term Nicotinamide Riboside Use Improves Coordination and Eye Movements in Ataxia Telangiectasia.

TNF-α-dependent neuronal necroptosis regulated in Alzheimer's disease by coordination of RIPK1-p62 complex with autophagic UVRAG.

Turning up the NAD<sup>+</sup>-mitophagy axis to treat Alzheimer's disease.

P. edulis Extract Protects Against Amyloid-β Toxicity in Alzheimer's Disease Models Through Maintenance of Mitochondrial Homeostasis via the FOXO3/DAF-16 Pathway.

Crosstalk among DNA Damage, Mitochondrial Dysfunction, Impaired Mitophagy, Stem Cell Attrition, and Senescence in the Accelerated Ageing Disorder Werner Syndrome.

A comprehensive AI‐driven analysis of large‐scale omic datasets reveals novel dual‐purpose targets for the treatment of cancer and aging.

Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD<sup>+</sup> signaling.

DNA polymerase β decrement triggers death of olfactory bulb cells and impairs olfaction in a mouse model of Alzheimer's disease.