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Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis.
- Published in:
- 2010
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- Publication type:
- Correction Notice
Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis.
- Published in:
- 2010
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- Publication type:
- journal article
Interactions of HIV-1 Proteins with Human T-Cell Cyclophilin A.
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- Annals of the New York Academy of Sciences, 1996, v. 782, n. 1, p. 456, doi. 10.1111/j.1749-6632.1996.tb40583.x
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- Publication type:
- Article
The Cleavage of the Bait Region of α<sub>2</sub>-Macroglobulin by Human Immunodeficiency Virus Proteinases and by Astacin.
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- Annals of the New York Academy of Sciences, 1994, v. 737, n. 1, p. 431, doi. 10.1111/j.1749-6632.1994.tb44332.x
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- Article
4,5,6-Trisubstituted Piperidinones as Conformationally Restricted Ceramide Analogues: Synthesis and Evaluation as Inhibitors of Sphingosine and Ceramide Kinases and as NKT Cell-Stimulatory Antigens.
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- Chemistry & Biodiversity, 2009, v. 6, n. 10, p. 1688, doi. 10.1002/cbdv.200900045
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- Article
Synthesis and Evaluation of Sphingolipid Analogues.
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- Chemistry & Biodiversity, 2009, v. 6, n. 5, p. 705, doi. 10.1002/cbdv.200900013
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- Publication type:
- Article
Synthesis of 7-Aza- and 7-Thiasphingosines, and Evaluation of Their Interaction with Sphingosine Kinases and with T-Cells.
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- Chemistry & Biodiversity, 2009, v. 6, n. 5, p. 725, doi. 10.1002/cbdv.200900039
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- Publication type:
- Article
Pimecrolimus permeates less than tacrolimus through normal, inflamed, or corticosteroid-pretreated skin.
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- Experimental Dermatology, 2005, v. 14, n. 10, p. 752, doi. 10.1111/j.1600-0625.2005.00354.x
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- Publication type:
- Article
The effect of topical pimecrolimus on keratoconjunctivitis sicca and chronic superficial keratitis in dogs: results from an exploratory study.
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- Veterinary Ophthalmology, 2005, v. 8, n. 1, p. 39, doi. 10.1111/j.1463-5224.2005.04062.x
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- Publication type:
- Article
Partial Deficiency of Sphingosine-1-Phosphate Lyase Confers Protection in Experimental Autoimmune Encephalomyelitis.
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- PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0059630
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- Publication type:
- Article
Confocal Fluorescence Detection Expanded to UV Excitation: The First Continuous Fluorimetric Assay of Human Steroid Sulfatase in Nanoliter Volume.
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- Assay & Drug Development Technologies, 2004, v. 2, n. 1, p. 21
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- Publication type:
- Article
Cage Dimeric N-Acyl- and N-Acyloxy-4-aryl-1,4-dihydropyridines as First Representatives of a Novel Class of HIV-1 Protease Inhibitors.
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- Archiv der Pharmazie, 1999, v. 332, n. 11, p. 380, doi. 10.1002/(SICI)1521-4184(199911)332:11<380::AID-ARDP380>3.0.CO;2-T
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- Publication type:
- Article
Cage Dimeric 4-Aryl-1,4-dihydropyridines as Promising Lead Structures for the Development of a Novel Class of HIV-1 Protease Inhibitors.
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- Archiv der Pharmazie, 1999, v. 332, n. 1, p. 3, doi. 10.1002/(SICI)1521-4184(19991)332:1<3::AID-ARDP3>3.0.CO;2-1
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- Publication type:
- Article
Synthesis of β3-Homophenylalanine-Derived Amino Acids and Peptides by Suzuki Coupling in Solution and on Solid Support.
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- Helvetica Chimica Acta, 2006, v. 89, n. 7, p. 1427
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- Publication type:
- Article
Interferon regulatory factor 5 and nuclear factor kappa‐B exhibit cooperating but also divergent roles in the regulation of pro‐inflammatory cytokines important for the development of TH1 and TH17 responses.
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- FEBS Journal, 2018, v. 285, n. 16, p. 3097, doi. 10.1111/febs.14600
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- Publication type:
- Article
Steroid sulfatase inhibitors.
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- Medicinal Research Reviews, 2004, v. 24, n. 4, p. 529, doi. 10.1002/med.20008
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- Publication type:
- Article
Pharmacological Inhibition of Stearoyl CoA Desaturase in the Skin Induces Atrophy of the Sebaceous Glands.
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- Journal of Investigative Dermatology, 2013, v. 133, n. 8, p. 2091, doi. 10.1038/jid.2013.89
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- Publication type:
- Article
Steroid Sulfatase in the Human Hair Follicle Concentrates in the Dermal Papilla.
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- Journal of Investigative Dermatology, 2001, v. 117, n. 6, p. 1342, doi. 10.1046/j.0022-202X.2001.01547.x
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- Publication type:
- Article
Ovalbumin-induced plasma interleukin-4 levels are reduced in ceramide kinase-deficient DO11.10 RAG1<sup>-/-</sup> mice.
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- Lipids in Health & Disease, 2010, v. 9, p. 1, doi. 10.1186/1476-511X-9-1
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- Publication type:
- Article
Synthesis and Biological Evaluation of New Triazolo- and Imidazolopyridine RORγt Inverse Agonists.
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- ChemMedChem, 2016, v. 11, n. 24, p. 2640, doi. 10.1002/cmdc.201600500
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- Publication type:
- Article
Cover Picture: BZM055, an Iodinated Radiotracer Candidate for PET and SPECT Imaging of Myelin and FTY720 Brain Distribution (ChemMedChem 4/2011).
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- ChemMedChem, 2011, v. 6, n. 4, p. 573, doi. 10.1002/cmdc.201190010
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- Publication type:
- Article
BZM055, an Iodinated Radiotracer Candidate for PET and SPECT Imaging of Myelin and FTY720 Brain Distribution.
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- ChemMedChem, 2011, v. 6, n. 4, p. 667, doi. 10.1002/cmdc.201000477
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- Publication type:
- Article
Phosphorylation by Sphingosine Kinase 2 is Essential for in vivo Potency of FTY720 Analogues.
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- ChemMedChem, 2008, v. 3, n. 7, p. 1027, doi. 10.1002/cmdc.200800037
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- Publication type:
- Article
Synthesis and Immobilization of erythro-C14-ω-Aminosphingosine-1-phosphate as a Potential Tool for Affinity Chromatography.
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- ChemMedChem, 2008, v. 3, n. 2, p. 356, doi. 10.1002/cmdc.200700285
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- Publication type:
- Article
FTY720-phosphate is dephosphorylated by lipid phosphate phosphatase 3
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- FEBS Letters, 2007, v. 581, n. 16, p. 3063, doi. 10.1016/j.febslet.2007.05.069
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- Publication type:
- Article
Reduced Activity of Sphingosine-1-Phosphate Lyase Induces Podocyte-related Glomerular Proteinuria, Skin Irritation, and Platelet Activation.
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- Toxicologic Pathology, 2015, v. 43, n. 5, p. 694, doi. 10.1177/0192623314565650
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- Article
Corrigendum: Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors.
- Published in:
- 2009
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- Publication type:
- Correction Notice
Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors.
- Published in:
- Nature Chemical Biology, 2009, v. 5, n. 6, p. 428, doi. 10.1038/nchembio.173
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- Publication type:
- Article
Pharmacological inhibition of RORγt suppresses the Th17 pathway and alleviates arthritis in vivo.
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- PLoS ONE, 2017, v. 12, n. 11, p. 1, doi. 10.1371/journal.pone.0188391
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- Publication type:
- Article
α<sub>2</sub>-Macroglobulin is Cleaved by HIV-1 Protease in the Bait Region but not in the C-Terminal Inter-Domain Region.
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- Biological Chemistry, 1991, v. 372, n. 2, p. 1051
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- Publication type:
- Article
Purification, Assay and Kinetic Features of HIV-1 Proteinase.
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- Biological Chemistry, 1990, v. 371, n. 1, p. 265
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- Publication type:
- Article
Destruction of Ethidium Bromide in Solution by Ozonolysis.
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- Biological Chemistry, 1988, v. 369, n. 2, p. 1191
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- Publication type:
- Article
Monoclonal Antibodies to the Multienzyme Enniatin Synthetase.
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- Biological Chemistry, 1987, v. 368, n. 1, p. 521
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- Publication type:
- Article
Nucleoside Phosphotransferase from Malt Sprouts.
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- Biological Chemistry, 1986, v. 367, n. 1, p. 291
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- Publication type:
- Article
Nucleoside Phosphotransferase from Malt Sprouts.
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- Biological Chemistry, 1986, v. 367, n. 1, p. 279
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- Publication type:
- Article
Nucleoside Phosphotransferase from Malt Sprouts.
- Published in:
- Biological Chemistry, 1986, v. 367, n. 1, p. 267
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- Publication type:
- Article