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LUBAC synthesizes linear ubiquitin chains via a thioester intermediate.
Published in:
EMBO Reports, 2012, v. 13, n. 9, p. 840, doi. 10.1038/embor.2012.105
By:
- Stieglitz, Benjamin;
- Morris-Davies, Aylin C;
- Koliopoulos, Marios G;
- Christodoulou, Evangelos;
- Rittinger, Katrin
Publication type:
Article
The Biophysical Characterisation and SAXS Analysis of Human NLRP1 Uncover a New Level of Complexity of NLR Proteins.
Published in:
PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0164662
By:
- Martino, Luigi;
- Holland, Louise;
- Christodoulou, Evangelos;
- Kunzelmann, Simone;
- Esposito, Diego;
- Rittinger, Katrin
Publication type:
Article
The Arabidopsis (ASHH2) CW domain binds monomethylated K4 of the histone H3 tail through conformational selection.
Published in:
FEBS Journal, 2020, v. 287, n. 20, p. 4458, doi. 10.1111/febs.15256
By:
- Dobrovolska, Olena;
- Brilkov, Maxim;
- Madeleine, Noelly;
- Ødegård‐Fougner, Øyvind;
- Strømland, Øyvind;
- Martin, Stephen R.;
- De Marco, Valeria;
- Christodoulou, Evangelos;
- Teigen, Knut;
- Isaksson, Johan;
- Underhaug, Jarl;
- Reuter, Nathalie;
- Aalen, Reidunn B.;
- Aasland, Rein;
- Halskau, Øyvind
Publication type:
Article
Small Molecule Inhibitor Targeting CDT1/Geminin Protein Complex Promotes DNA Damage and Cell Death in Cancer Cells.
Published in:
Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.860682
By:
- Karantzelis, Nikolaos;
- Petropoulos, Michalis;
- De Marco, Valeria;
- Egan, David A.;
- Fish, Alexander;
- Christodoulou, Evangelos;
- Will, David W.;
- Lewis, Joe D.;
- Perrakis, Anastassis;
- Lygerou, Zoi;
- Taraviras, Stavros
Publication type:
Article
Structural basis of lentiviral subversion of a cellular protein degradation pathway.
Published in:
Nature, 2014, v. 505, n. 7482, p. 234, doi. 10.1038/nature12815
By:
- Schwefel, David;
- Groom, Harriet C. T.;
- Boucherit, Virginie C.;
- Christodoulou, Evangelos;
- Walker, Philip A.;
- Stoye, Jonathan P.;
- Bishop, Kate N.;
- Taylor, Ian A.
Publication type:
Article
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP.
Published in:
Nature, 2013, v. 503, n. 7476, p. 422, doi. 10.1038/nature12638
By:
- Stieglitz, Benjamin;
- Rana, Rohini R.;
- Koliopoulos, Marios G.;
- Morris-Davies, Aylin C.;
- Schaeffer, Veronique;
- Christodoulou, Evangelos;
- Howell, Steven;
- Brown, Nicholas R.;
- Dikic, Ivan;
- Rittinger, Katrin
Publication type:
Article
HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase.
Published in:
Nature, 2011, v. 480, n. 7377, p. 379, doi. 10.1038/nature10623
By:
- Goldstone, David C.;
- Ennis-Adeniran, Valerie;
- Hedden, Joseph J.;
- Groom, Harriet C. T.;
- Rice, Gillian I.;
- Christodoulou, Evangelos;
- Walker, Philip A.;
- Kelly, Geoff;
- Haire, Lesley F.;
- Yap, Melvyn W.;
- de Carvalho, Luiz Pedro S.;
- Stoye, Jonathan P.;
- Crow, Yanick J.;
- Taylor, Ian A.;
- Webb, Michelle
Publication type:
Article
Understanding heterologous protein overproduction under the T7 promoter: A practical exercise.
Published in:
Biochemistry & Molecular Biology Education, 2002, v. 30, n. 3, p. 189, doi. 10.1002/bmb.2002.494030030066
By:
- Christodoulou, Evangelos;
- Vorgias, Constantinos E.
Publication type:
Article
Target highlights in CASP9: Experimental target structures for the critical assessment of techniques for protein structure prediction.
Published in:
Proteins, 2011, v. 79, p. 6, doi. 10.1002/prot.23196
By:
- Kryshtafovych, Andriy;
- Moult, John;
- Bartual, Sergio G.;
- Bazan, J. Fernando;
- Berman, Helen;
- Casteel, Darren E.;
- Christodoulou, Evangelos;
- Everett, John K.;
- Hausmann, Jens;
- Heidebrecht, Tatjana;
- Hills, Tanya;
- Hui, Raymond;
- Hunt, John F.;
- Seetharaman, Jayaraman;
- Joachimiak, Andrzej;
- Kennedy, Michael A.;
- Kim, Choel;
- Lingel, Andreas;
- Michalska, Karolina;
- Montelione, Gaetano T.
Publication type:
Article
Activation loop phosphorylation and cGMP saturation of PKG regulate egress of malaria parasites.
Published in:
PLoS Pathogens, 2024, v. 20, n. 6, p. 1, doi. 10.1371/journal.ppat.1012360
By:
- Koussis, Konstantinos;
- Haase, Silvia;
- Withers-Martinez, Chrislaine;
- Flynn, Helen R.;
- Kunzelmann, Simone;
- Christodoulou, Evangelos;
- Ibrahim, Fairouz;
- Skehel, Mark;
- Baker, David A.;
- Blackman, Michael J.
Publication type:
Article
Corrigendum: The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin.
Published in:
Nature Communications, 2014, v. 5, n. 5, p. 4031, doi. 10.1038/ncomms5031
By:
- Withers-Martinez, Chrislaine;
- Strath, Malcolm;
- Hackett, Fiona;
- Haire, Lesley F.;
- Howell, Steven A.;
- Walker, Philip A.;
- Christodoulou, Evangelos;
- Dodson, Guy G.;
- Blackman, Michael J.
Publication type:
Article
The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin.
Published in:
Nature Communications, 2014, v. 5, n. 5, p. 3726, doi. 10.1038/ncomms4726
By:
- Withers-Martinez, Chrislaine;
- Strath, Malcolm;
- Hackett, Fiona;
- Haire, Lesley F.;
- Howell, Steven A.;
- Walker, Philip A.;
- Evangelos, Christodoulou;
- Dodson, Guy G.;
- Blackman, Michael J.
Publication type:
Article
Axial pullout strength comparison of different screw designs: fenestrated screw, dual outer diameter screw and standard pedicle screw.
Published in:
Scoliosis (17487161), 2015, v. 10, n. 1, p. 1, doi. 10.1186/s13013-015-0039-6
By:
- Christodoulou, Evangelos;
- Chinthakunta, Suresh;
- Reddy, Divya;
- Khalil, Saif;
- Apostolou, Thomas;
- Drees, Philipp;
- Kafchitsas, Konstantinos
Publication type:
Article
High-resolution X-ray structure of the DNA-binding protein HU from the hyper-thermophilic Thermotoga maritima and the determinants of its thermostability.
Published in:
Extremophiles, 2003, v. 7, n. 2, p. 111, doi. 10.1007/s00792-002-0302-7
By:
- Christodoulou, Evangelos;
- Rypniewski, Wojciech R.;
- Vorgias, Constantinos E.
Publication type:
Article
The thermostability of DNA-binding protein HU from mesophilic, thermophilic, and extreme thermophilic bacteria.
Published in:
Extremophiles, 2002, v. 6, n. 1, p. 21, doi. 10.1007/s007920100235
By:
- Christodoulou, Evangelos;
- Vorgias, Constantinos E.
Publication type:
Article
The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1.
Published in:
Nucleic Acids Research, 2011, v. 39, n. 13, p. 5715, doi. 10.1093/nar/gkr125
By:
- Heidebrecht, Tatjana;
- Christodoulou, Evangelos;
- Chalmers, Michael J.;
- Jan, Sabrina;
- ter Riet, Bas;
- Grover, Rajesh K.;
- Joosten, Robbie P.;
- Littler, Dene;
- van Luenen, Henri;
- Griffin, Patrick R.;
- Wentworth, Paul;
- Borst, Piet;
- Perrakis, Anastassis
Publication type:
Article
The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase.
Published in:
Nucleic Acids Research, 2007, v. 35, n. 7, p. 2107, doi. 10.1093/nar/gkm049
By:
- Yu, Zhong;
- Genest, Paul-André;
- ter Riet, Bas;
- Sweeney, Kate;
- DiPaolo, Courtney;
- Kieft, Rudo;
- Christodoulou, Evangelos;
- Perrakis, Anastassis;
- Simmons, Jana M.;
- Hausinger, Robert P.;
- van Luenen, Henri G.A.M.;
- Rigden, Daniel J.;
- Sabatini, Robert;
- Borst, Piet
Publication type:
Article
Structural basis of substrate discrimination and integrin binding by autotaxin.
Published in:
Nature Structural & Molecular Biology, 2011, v. 18, n. 2, p. 198, doi. 10.1038/nsmb.1980
By:
- Hausmann, Jens;
- Kamtekar, Satwik;
- Christodoulou, Evangelos;
- Day, Jacqueline E.;
- Tao Wu;
- Fulkerson, Zachary;
- Albers, Harald M. H. G.;
- van Meeteren, Laurens A.;
- Houben, Anna J. S.;
- van Zeijl, Leonie;
- Jansen, Silvia;
- Andries, Maria;
- Hall, Troii;
- Pegg, Lyle E.;
- Benson, Timothy E.;
- Kasiem, Mobien;
- Harlos, Karl;
- Kooi, Craig W. Vander;
- Smyth, Susan S.;
- Ovaa, Huib
Publication type:
Article
Chemical genetic identification of CDKL5 substrates reveals its role in neuronal microtubule dynamics.
Published in:
EMBO Journal, 2018, v. 37, n. 24, p. N.PAG, doi. 10.15252/embj.201899763
By:
- Baltussen, Lucas L;
- Negraes, Priscilla D;
- Silvestre, Margaux;
- Claxton, Suzanne;
- Moeskops, Max;
- Christodoulou, Evangelos;
- Flynn, Helen R;
- Snijders, Ambrosius P;
- Muotri, Alysson R;
- Ultanir, Sila K
Publication type:
Article
Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity.
Published in:
EMBO Journal, 2016, v. 35, n. 11, p. 1204, doi. 10.15252/embj.201593741
By:
- Koliopoulos, Marios G;
- Esposito, Diego;
- Christodoulou, Evangelos;
- Taylor, Ian A;
- Rittinger, Katrin
Publication type:
Article
Ubiquitin activation is essential for schizont maturation in Plasmodium falciparum blood-stage development.
Published in:
PLoS Pathogens, 2020, v. 16, n. 6, p. 1, doi. 10.1371/journal.ppat.1008640
By:
- Green, Judith L.;
- Wu, Yang;
- Encheva, Vesela;
- Lasonder, Edwin;
- Prommaban, Adchara;
- Kunzelmann, Simone;
- Christodoulou, Evangelos;
- Grainger, Munira;
- Truongvan, Ngoc;
- Bothe, Sebastian;
- Sharma, Vikram;
- Song, Wei;
- Pinzuti, Irene;
- Uthaipibull, Chairat;
- Srichairatanakool, Somdet;
- Birault, Veronique;
- Langsley, Gordon;
- Schindelin, Hermann;
- Stieglitz, Benjamin;
- Snijders, Ambrosius P.
Publication type:
Article

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