We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Neuroscience in the era of functional genomics and systems biology.
- Authors
Geschwind, Daniel H.; Konopka, Genevieve
- Abstract
Advances in genetics and genomics have fuelled a revolution in discovery-based, or hypothesis-generating, research that provides a powerful complement to the more directly hypothesis-driven molecular, cellular and systems neuroscience. Genetic and functional genomic studies have already yielded important insights into neuronal diversity and function, as well as disease. One of the most exciting and challenging frontiers in neuroscience involves harnessing the power of large-scale genetic, genomic and phenotypic data sets, and the development of tools for data integration and mining. Methods for network analysis and systems biology offer the promise of integrating these multiple levels of data, connecting molecular pathways to nervous system function.
- Subjects
NEUROSCIENCES; GENOMICS; SYSTEMS biology; BIOINFORMATICS; NEURONS; NEUROINFORMATICS; GENETICS; GRAPH theory; BIOLOGICAL systems; COMPUTATIONAL neuroscience
- Publication
Nature, 2009, Vol 461, Issue 7266, p908
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/nature08537