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- Title
Analysis of the Absence of the Detrusor Muscle in Initial Transurethral Resected Specimens and the Presence of Residual Tumor Tissue.
- Authors
Huang, Jiefu; Fu, Jinggao; Zhan, Hailun; Xie, Keji; Liu, Bolong; Yang, Fei; Lu, Yangbo; Zhou, Xiangfu
- Abstract
Objective: To investigate the relationship between surgeon's experience, tumor characteristics, absent detrusor muscle (DM) tissue in resected specimens, and residual tumor after an initial transurethral resection. Patients and Methods: We conducted an analysis of 216 patients from two centers over a 3-year period. Patients with primary bladder tumors that were judged to have been completely resected were recruited. The data included tumor characteristics, surgeon category, and DM status. Logistic regression multivariate analyses were conducted. Results: Large tumors, lateral/dome/anterior wall tumors, and surgery performed by junior surgeons were independently associated with absent DM. Large tumors, dome/anterior wall tumors, T1 and absent DM were independently associated with residual disease. The absence and presence of the DM were associated with residual tumor rates of 51.8 and 20.9%, respectively (OR 15.537). Resection by senior surgeons was associated with the presence of DM and clean resection (OR 0.274 and 0.141, respectively). Conclusions: Absent DM and residual tumor were more likely to occur in cases involving large tumors that were located in the lateral/dome/anterior wall, especially when the surgery was performed by a junior surgeon. Absent DM appears to be a surrogate marker for residual disease. Copyright © 2012 S. Karger AG, Basel
- Subjects
BLADDER cancer treatment; OVERACTIVE bladder; TRANSURETHRAL prostatectomy; CANCER cells; SURGEONS; BIOMARKERS; SURGICAL excision
- Publication
Urologia Internationalis, 2012, Vol 89, Issue 3, p319
- ISSN
0042-1138
- Publication type
Article
- DOI
10.1159/000341103