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- Title
Novel Insights in Fetal Cardiomyopathy due to in utero Herpes Simplex Virus Infection.
- Authors
Pahlitzsch, Tamara Margit Jutta; Helbig, Elisa Theresa; Sarioglu, Nanette; Hinkson, Larry; von Weizsäcker, Katharina; Henrich, Wolfgang
- Abstract
This is a case report of fatal cardiomyopathy in a fetus following maternal intrauterine infection with herpes simplex virus (HSV), despite the mother having no symptoms of an infection. The fetus showed signs of a disseminated infection affecting the heart, brain, lungs, liver, adrenal glands, and skin. HSV cardiomyopathy, characterized by vast necrosis, extensive calcifications, and inflammatory infiltration, was found to be the cause of intrauterine fetal death. To our knowledge, this is a unique report of an asymptomatic maternal nonprimary or recurrent HSV infection that induced a transmission of HSV resulting in extensive and fatal changes in the fetal heart.
- Subjects
CARDIOMYOPATHIES; PREGNANCY complications; HERPES simplex treatment; CALCIFICATION; FETAL heart abnormalities
- Publication
Fetal Diagnosis & Therapy, 2017, Vol 42, Issue 3, p236
- ISSN
1015-3837
- Publication type
journal article
- DOI
10.1159/000475814