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- Title
Does a Myelomeningocele Sac Compared to No Sac Result in Decreased Postnatal Leg Function following Maternal Fetal Surgery for Spina Bifida Aperta?
- Authors
Wilson, R. Douglas; Johnson, Mark P.; Bebbington, Michael; Flake, Alan W.; Hedrick, Holly L.; Sutton, Leslie N.; Adzick, N. Scott
- Abstract
Objective: A fetus with large sac S1 myelomeningocele (MMC) but bilateral talipes prompted the question, ‘Does the presence or size of an MMC sac affect postnatal leg function?’ Study Design: An MMC database with prenatal, birth, and a minimum of 1-year follow-up evaluation was reviewed. All fetuses had in-utero MMC repair at 20 + 0 to 25 + 6 weeks at a single institution. Fifty-four fetuses had prenatal evaluation, with 48 children completing a birth and a 1-year evaluation of leg function. Results: An MMC sac was present in 38/54 (70%) of fetuses evaluated in-utero and had been present in 35/48 (73%) of children evaluated at 1 year of age. Although leg function evaluated at 1 year was better than expected in the ‘no sac’ group (p = 0.059), this did not reach statistical significance. Conclusion: The presence of an MMC sac may increase postnatal lower limb morbidity. Copyright © 2007 S. Karger AG, Basel
- Subjects
FETAL surgery; OBSTETRICS; MYELOMENINGOCELE; SPINA bifida; SPINAL cord abnormalities
- Publication
Fetal Diagnosis & Therapy, 2007, Vol 22, Issue 5, p348
- ISSN
1015-3837
- Publication type
Article
- DOI
10.1159/000103294