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- Title
Individualized surgical treatment in patients with advanced gastrointestinal stromal tumor -- a case series.
- Authors
Pytlos, Jakub; Pałucki, Jakub; Lenarcik, Małgorzata; Pierzankowski, Ireneusz; Klimczak, Anna; Olesiński, Tomasz
- Abstract
In this case series we present the cases of two patients at a metastatic stage of stomach gastrointestinal stromal tumor, who received treatment with imatinib. After a period of disease stability patients showed signs of resistance to the first-line therapy and despite the promising switch to sunitinib, developed life-threatening complications. Salvage surgeries were performed, aimed at preserving patients life and simultaneously reducing the tumor mass. Operation greatly improved patients condition and allowed for successful continuation of tyrosine kinase inhibitor treatment, showing that surgery should be considered a viable complement to the chemotherapeutical treatment.
- Subjects
GASTROINTESTINAL stromal tumors; IMATINIB; SALVAGE therapy; CANCER chemotherapy; SUNITINIB
- Publication
Oncology in Clinical Practice (2450-1654), 2023, Vol 19, Issue 5, p384
- ISSN
2450-1654
- Publication type
Article
- DOI
10.5603/OCP.2023.0023