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- Title
Antidiabetic and antioxidant properties of nine medicinal and aromatic plants extracts: Inhibition of key enzymes linked to type-2 diabetes.
- Authors
Arslan, Hülya Şen; Çam, Mustafa
- Abstract
The study aimed to determine enzyme inhibitory activities and bioactive features of the methanol extracts of peppermint (Mentha piperita L.), spearmint (Mentha spicata L.), yarrow (Achillea millefolium L.), sage (Salvia officinalis L.), yellow cantoron (Hypericum perforatum L.), thyme (Thymus vulgaris L.), lavender (Lavandula angustifolia Mill.), lemon balm (Melissa officinalis L.) and echinacea (Echinacea purpurea L.). The methanol extraction was carried at 40 °C for 2 h. The inhibitory activities of plant extracts on antioxidant and α-glucosidase, α-amylase and lipase enzymes were determined. The antioxidant activities of these extracts were determined by the methods of DPPH, ABTS and β-carotene-bleaching test (βC). The results showed that peppermint significantly (p<0.05) inhibited the activity of α-glucosidase (IC50: 1.18 ± 1.079 mg/mL) and DPPH free radical scavenging activity (EC50: 2.36 ± 0.3). Total phenolic content (TPC) and total flavonoid content (TFC) of the extracts were between 3.06-31.13 mg gallic acid equivalents (GAE) and 0.58-4.39 μg catechin equivalents (CE) per g of plant, respectively. It concluded that all the plant materials used in the study had inhibitory effect on α-glucosidase.
- Subjects
HYPOGLYCEMIC agents; ANTIOXIDANTS; MEDICINAL plants; AROMATIC plants; PLANT extracts; ENZYME inhibitors
- Publication
Journal of Agroalimentary Processes & Technologies, 2022, Vol 28, Issue 1, p27
- ISSN
2069-0053
- Publication type
Article