We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
ω-3 Polyunsaturated Fatty Acid Supplementation Does Not Influence Body Composition, Insulin Resistance, and Lipemia in Women With Type 2 Diabetes and Obesity.
- Authors
Crochemore, Izabella Candido Carvalho; Souza, Aline F. P.; de Souza, Andressa C. F.; Rosado, Eliane Lopes
- Abstract
To evaluate the influence of ω-3 polyunsaturated fatty acid (ω-3 PUFA) supplementation on body composition, insulin resistance, and lipemia of women with type 2 diabetes, the authors evaluated 41 women (60.64 ± 7.82 years) with high blood pressure and diabetes mellitus in a randomized and single-blind longitudinal intervention study. The women were divided into 3 groups: GA (2.5 g/d fish oil), GB (1.5 g/d fish oil), and GC (control). The capsules with the supplement contained 21.9% of eicosapentaenoic acid and 14.1% of docosapentaenoic acid. Biochemical (glucose, glycated hemoglobin, total and fractional cholesterol, triglycerides, and insulin) and anthropometric (body mass, stature, waist circumference [WC], and body composition) evaluations were performed before and after the 30 days of intervention. Homeostasis model assessment–insulin resistance and the Quantitative Insulin Sensitivity Check Index were used to evaluate the insulin resistance and insulin sensitivity (IS), respectively. GB presented a greater loss of body mass and WC (P < .05), greater frequency of glycemic and total cholesterol reduction, and an increase of high-density lipoprotein cholesterol compared with GA. Thus, a high dose of ω-3 PUFA can reduce IS. A lower dose of ω-3 PUFA positively influenced body composition and lipid metabolism.
- Subjects
BRAZIL; BLOOD sugar analysis; TYPE 2 diabetes treatment; ANTHROPOMETRY; BODY composition; CHOLESTEROL; DIETARY supplements; DOSE-effect relationship in pharmacology; FISH oils; GLYCOSYLATED hemoglobin; HYPERTENSION; BIOELECTRIC impedance; INSULIN; INSULIN resistance; OBESITY; OMEGA-3 fatty acids; HEALTH outcome assessment; RESEARCH funding; STATISTICAL sampling; STATISTICS; TRIGLYCERIDES; U-statistics; WOMEN'S health; COMORBIDITY; EICOSAPENTAENOIC acid; DATA analysis; BODY mass index; TREATMENT effectiveness; PRE-tests &; post-tests; BLIND experiment; DATA analysis software; WAIST circumference; DESCRIPTIVE statistics
- Publication
Nutrition in Clinical Practice, 2012, Vol 27, Issue 4, p553
- ISSN
0884-5336
- Publication type
Article
- DOI
10.1177/0884533612444535