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- Title
Pancreatic resection in patients with synchronous extra‐pancreatic malignancy: outcomes and complications.
- Authors
Mehta, Shreya; Tan, Grace I.; Nahm, Christopher B.; Chua, Terence C.; Pearson, Andrew; Gill, Anthony J.; Samra, Jaswinder S.; Mittal, Anubhav
- Abstract
Background: Patients may present with a resectable pancreatic tumour in the context of a concurrent primary extra‐pancreatic malignancy. These patients pose a dilemma regarding their suitability for surgery. We evaluated our experience with such patients who underwent pancreatic resection with curative intent and detailed their outcomes and rationale for surgical decision‐making. Methods: A retrospective review of patients with pancreatic concurrent extra‐pancreatic primary malignancy who underwent pancreatic resection at our institution over a 12‐year period (2005–2016) was performed. Clinical, histopathological and perioperative outcomes were reviewed. Results: Ten patients with a median age of 74 years (40–85 years) were identified. Secondary primary tumours included thyroid (n = 2), gastrointestinal (n = 4), small bowel neuroendocrine (n = 1), renal (n = 1) and haematological malignancies (n = 2). Pancreatic tumours included pancreatic ductal adenocarcinomas (n = 6), solid pseudopapillary neoplasms (n = 2) and ampullary carcinomas (n = 2). After a median follow up of 41.3 months (31.3–164 months), 8 of 10 patients were still alive. Two patients died due to metastatic disease from the secondary malignancy (small bowel neuroendocrine tumour and sigmoid colon adenocarcinoma). The post‐operative complication rate was 30% with no perioperative 90‐day mortality. Conclusion: Selected patients with a pancreatic and concurrent primary extra‐pancreatic malignancy may undergo curative pancreatic resection with favourable outcomes.
- Subjects
PANCREATIC surgery; SIGMOID colon; TERMINALLY ill; TUMORS
- Publication
ANZ Journal of Surgery, 2020, Vol 90, Issue 3, p290
- ISSN
1445-1433
- Publication type
Article
- DOI
10.1111/ans.15651