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- Title
ACTIVITIES OF SULFHYDRYL OXIDASE AND XANTHINE OXIDOREDUCTASE SYSTEM IN SALIVA AND SERUM OF WOMEN WITH DIFFERENT TYPES OF BREAST TUMORS.
- Authors
Jabbar, Samar Ahmed; Hasan, Hathama Razooki
- Abstract
Breast tumors are spread among women. It is a type of diseases in which the division and the modification of cells in breast tissues are uncontrolled mostly, typically resulting in a lump, or mass. This study aims to evaluate the activities of sulfhydryl oxidase and xanthine oxidoreductase system in the saliva and serum of women with different types of tumors and to shed the light on the possibility of use the saliva instead of the blood to follow up these activities for diagnosis this type of disease and its progress. Iraqi women with benign breast tumors (n=32), Iraqi women with newly dragonized breast cancer (n=32), as well as age matched Iraqi healthy women (n=27) were the participants of the current study. The studied parameters included: measurement of the activities of Quiescin- sulfhydryl oxidase1 and xanthine-oxidoreductase system in serum and saliva samples of the participants. The results indicated the presence of highly increase in both saliva and serum Quiescin – sulfhydryl oxidase activity as well as xanthine oxidase activities in the women with benign tumors and those with breast cancer in comparison with their corresponding fluid of the healthy women( P=0.0001). Meanwhile, the activity of xanthine dehydrogenase exhibit a decreased activity in the diseased groups in comparison with that of the control healthy group (P=0.0001). Furthermore the present study indicated that there is no correlation between the changes in the studied parameters in the serum and the saliva of all the studied groups.
- Subjects
SULFHYDRYL oxidases; XANTHINE oxidase; OXIDOREDUCTASES; BREAST tumor treatment; CANCER treatment
- Publication
Biochemical & Cellular Archives, 2021, Vol 21, p2019
- ISSN
0972-5075
- Publication type
Article