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- Title
Anti-Inflammatory Activity of Copao ( Eulychnia Acida Phil., Cactaceae) Fruits.
- Authors
Jiménez-Aspee, Felipe; Alberto, Maria; Quispe, Cristina; Caramantin Soriano, Maria; Theoduloz, Cristina; Zampini, Iris; Isla, Maria; Schmeda-Hirschmann, Guillermo
- Abstract
Copao ( Eulychnia acida Phil., Cactaceae) is an endemic species occurring in northern Chile. The edible fruits of this plant are valued for its acidic and refreshing taste. Phenolic-enriched extracts from copao fruit pulp and epicarp, collected in the Elqui and Limari river valleys, were assessed by its in vitro ability to inhibit the pro-inflammatory enzymes lipoxygenase (LOX) and cyclooxygenases (COX-1 and COX-2). At 100 μg/mL, pulp extracts showed better effect towards LOX than epicarp extract, while COX-2 inhibition was observed for both epicarp and pulp samples. In general, the extracts were inactive towards COX-1. A positive correlation was observed between the anti-inflammatory activity and the main phenolic compounds found in this fruit. Copao fruits from the Limari valley, a main place of collection and commercialization, showed major activity, adding evidence on the possible health-beneficial effects of this native Chilean fruit.
- Subjects
ANTI-inflammatory agents; CACTUS; CYCLOOXYGENASES; PLANT extracts; LIPOXYGENASES; THERAPEUTICS
- Publication
Plant Foods for Human Nutrition, 2015, Vol 70, Issue 2, p135
- ISSN
0921-9668
- Publication type
Article
- DOI
10.1007/s11130-015-0468-7