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- Title
Oncomeric Profiles of microRNAs as New Therapeutic Targets for Treatment of Ewing's Sarcoma: A Composite Review.
- Authors
Hassan, Mubashir; Shahzadi, Saba; Malik, Amal; Din, Salah ud; Yasir, Muhammad; Chun, Wanjoo; Kloczkowski, Andrzej
- Abstract
Ewing's sarcoma is a rare type of cancer that forms in bones and soft tissues in the body, affecting mostly children and young adults. Current treatments for ES are limited to chemotherapy and/or radiation, followed by surgery. Recently, microRNAs have shown favourable results as latent diagnostic and prognostic biomarkers in various cancers. Furthermore, microRNAs have shown to be a good therapeutic agent due to their involvement in the dysregulation of various molecular pathways linked to tumour progression, invasion, angiogenesis, and metastasis. In this review, comprehensive data mining was employed to explore various microRNAs that might have therapeutic potential as target molecules in the treatment of ES.
- Subjects
EWING'S sarcoma; DRUG target; MICRORNA; PROGNOSIS; YOUNG adults
- Publication
Genes, 2023, Vol 14, Issue 10, p1849
- ISSN
2073-4425
- Publication type
Article
- DOI
10.3390/genes14101849