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- Title
Genital Ulcer Development in Patients with Acute Promyelocytic Leukaemia Treated with All-Trans Retinoic Acid: A Case Series.
- Authors
Al Huneini, Mohammed; Wasim, Fauzia; Al Farsi, Khalil; Al-Khabori, Murtadha; Al Kindi, Salam
- Abstract
We report here four cases of genital ulcers that developed after the administration of all-trans retinoic acid (ATRA) for the treatment of acute promyelocytic leukemia (APL). Between October 2007 and March 2010, three males and one female (age range 19-35 years) were identified to have genital ulcers after being prescribed all-trans retinoic acid (ATRA) as a part of chemotherapy for APL. This is the first series of cases describing genital ulcers, as a unique and rare complication of ATRA used for treatment of APL in these patients, with no other cause identified. Following temporary cessation of ATRA for a few days in these three cases, improvement of the ulcers was noted.
- Subjects
DRUG side effects; FEVER; TRETINOIN; ULCERS; ACUTE promyelocytic leukemia; DISEASE complications
- Publication
Oman Medical Journal, 2013, Vol 28, Issue 3, p207
- ISSN
1999-768X
- Publication type
Article
- DOI
10.5001/omj.2013.56