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- Title
COVID-19 Infection in Sickle Cell Patients in a Developing Country: A Case Series.
- Authors
Silva-Pinto, Ana Cristina; Santos-Oliveira, Letícia; Santos, Flávia Leite Souza; Kashima Haddad, Simone; De Santis, Gil Cunha; do Tocantins Calado, Rodrigo
- Abstract
Sickle cell disease is characterized by vaso-occlusive phenomena and haemolytic anaemia. There is a significant concern that the overlap of COVID-19 lung disease with acute chest syndrome that occurs in sickle cell patients may result in serious complications. Case reports of sickle cell patients with COVID-19 have been published. Here, we present a case series of COVID-19 infection in sickle cell patients in a developing country (Brazil). Only 10 patients tested positive so far for SARS-CoV-2 of 600 patients followed at our institution, of which 8 needed hospitalization (one in the intensive care unit), with no deaths. Even in a middle-income country, COVID-19 was reported to be relatively mild in sickle cell patients. In relation to risk factors, blood type O seems to confer some protection against developing severe COVID-19, a finding that could guide clinicians to adopt more clinical surveillance for patients with non-O blood type in sickle cell patients.
- Subjects
COVID-19; SICKLE cell anemia; DEVELOPING countries; BLOOD groups; HEMOLYTIC anemia; MOYAMOYA disease
- Publication
Acta Haematologica, 2022, Vol 145, Issue 1, p1
- ISSN
0001-5792
- Publication type
Article
- DOI
10.1159/000519028