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- Title
Disseminated Strongyloides stercoralis Infection in HTLV-1-Associated Adult T-Cell Leukemia/Lymphoma.
- Authors
Stewart, Donn M.; Ramanathan, Roshan; Mahanty, Siddhartha; Fedorko, Daniel P.; Janik, John E.; Morris, John C.
- Abstract
A 55-year-old woman with human T-cell lymphotropic virus type-1 (HTLV-1)-associated adult T-cell leukemia (ATL) and a history of previously treated Strongyloides stercoralis infection received anti-CD52 monoclonal antibody therapy with alemtuzumab on a clinical trial. After an initial response, she developed ocular involvement by ATL. Alemtuzumab was stopped and high-dose corticosteroid therapy was started to palliate her ocular symptoms. Ten days later, the patient developed diarrhea, vomiting, fever, cough, skin rash, and a deteriorating mental status. She was diagnosed with disseminated S. stercoralis. Corticosteroids were discontinued and the patient received anthelmintic therapy with ivermectin and albendazole with complete clinical recovery. Copyright © 2011 S. Karger AG, Basel
- Subjects
HTLV diseases; ADULT T-cell leukemia; MONOCLONAL antibodies; LYMPHOMAS; ALBENDAZOLE
- Publication
Acta Haematologica, 2011, Vol 126, Issue 2, p63
- ISSN
0001-5792
- Publication type
Article
- DOI
10.1159/000324799