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- Title
Mechanical Carbohydrate Sensors Based on Soft Hydrogel Particles.
- Authors
Pussak, Daniel; Ponader, Daniela; Mosca, Simone; Ruiz, Salomé Vargas; Hartmann, Laura; Schmidt, Stephan
- Abstract
Elastic sensors: A simple method is presented for the measurement of specific biomolecular interactions with soft colloidal hydrogel particles (SCPs) as sensors. Carbohydrate/lectin interactions (see picture; green: carbohydrate molecules) were studied by optical detection of the mechanical deformation of the particles on a lectin surface. The affinity of various carbohydrate inhibitors could also be readily determined.
- Subjects
ORGANIC compounds; HYDROGELS; SURFACE plasmon resonance; ELECTRONIC probes; SYNERESIS; MICELLES
- Publication
Angewandte Chemie International Edition, 2013, Vol 52, Issue 23, p6084
- ISSN
1433-7851
- Publication type
Article
- DOI
10.1002/anie.201300469