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- Title
Speeding up Evolutionary Search by Small Fitness Fluctuations.
- Authors
Otwinowski, Jakub; Tanase-Nicola, Sorin; Nemenman, Ilya
- Abstract
We consider a fixed size population that undergoes an evolutionary adaptation in the weak mutation rate limit, which we model as a biased Langevin process in the genotype space. We show analytically and numerically that, if the fitness landscape has a small highly epistatic (rough) and time-varying component, then the population genotype exhibits a high effective diffusion in the genotype space and is able to escape local fitness minima with a large probability. We argue that our principal finding that even very small time-dependent fluctuations of fitness can substantially speed up evolution is valid for a wide class of models.
- Subjects
STATISTICAL methods in population biology; BIOLOGICAL adaptation; GENETIC mutation; LANGEVIN equations; GENOTYPE-environment interaction; EPISTASIS (Genetics); MAXIMA &; minima
- Publication
Journal of Statistical Physics, 2011, Vol 144, Issue 2, p367
- ISSN
0022-4715
- Publication type
Article
- DOI
10.1007/s10955-011-0199-6