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- Title
The Impact of Sex and Age on the Prevalence of Clinically Relevant Sensitization and Asymptomatic Sensitization in the General Population.
- Authors
Dor-Wojnarowska, Anna; Liebhart, Jerzy; Miecielica, Jadwiga; Rabski, Marek; Fal, Andrzej; Samoliński, Bolesław; Nittner-Marszalska, Marita
- Abstract
The objective of our study was to evaluate the impact of sex and age on the prevalence of sensitization to inhalant allergens. The study was performed as a part of Polish Epidemiology of Allergic Diseases study, and data concerning citizens of Wroclaw were analyzed. The participants were divided into three age groups (6-7, 13-14, and 20-44 years) with a subdivision according to sex. We randomly selected 1409 individuals, 439 people complied; the complete set of tests was performed on 421 of them. We found that 37.7 % of the study population demonstrated sensitization to at least one of the allergens tested. Positive skin tests were found more frequently in males than in females ( p = 0.003); among 6-7-year-old children, the sensitization was independent of sex ( p = 0.26), while in two other groups, it was higher in males ( p = 0.002 and p = 0.03, respectively). Clinically asymptomatic sensitization (AS) was found more often in females than in males ( p = 0.04). The higher rate of AS in women was observed only in the two younger age groups, while in the 20-44-year-old group AS did not differ between the sexes ( p = 0.72). Female sex hormones may contribute to a later change in the nature of sensitization from clinically asymptomatic to symptomatic. Further studies are needed to confirm the results of our study.
- Publication
Archivum Immunologiae & Therapiae Experimentalis, 2017, Vol 65, Issue 3, p253
- ISSN
0004-069X
- Publication type
Article
- DOI
10.1007/s00005-016-0425-7