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- Title
Germ cell malignancies of the ovary: treatment with vinblastine, actinomycin D, bleomycin and cisplatin containing chemotherapy combinations.
- Authors
Bradof, James E.; Hakes, Thomas B.; Ochoa, Manuel; Golbey, Robert; Bradof, J E; Hakes, T B; Ochoa, M; Golbey, R
- Abstract
Seventeen patients with malignant ovarian germ cell tumors were treated with vinblastine, actinomycin D, bleomycin and cisplatin containing combinations. Many of these patients were heavily pretreated. Thirteen patients had objectively measurable disease and ten (77%) had an objective response (CR or PR). Four patients had nonmeasurable disease or were treated in an adjuvant setting and all remain without evidence of disease. Extensive disease and poor performance status were poor prognostic factors. Induction portions of these treatment programs which contained cisplatin appeared most effective. Maintenance portions without cisplatin appeared less effective.
- Publication
Cancer (0008543X), 1982, Vol 50, Issue 6, p1070
- ISSN
0008-543X
- Publication type
journal article
- DOI
10.1002/1097-0142(19820915)50:6<1070::AID-CNCR2820500609>3.0.CO;2-M