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- Title
Alcohol drinking may not be a major risk factor for fatty liver in Japanese undergoing a health checkup.
- Authors
Yamada, Tamaki; Fukatsu, Mitsuru; Suzuki, Sadao; Yoshida, Takashi; Tokudome, Shinkan; Joh, Takashi
- Abstract
The question of whether alcohol drinking is a risk factor for fatty liver as shown by ultrasonography was investigated by both cross-sectional and longitudinal approaches in Japanese undergoing a health checkup. In this cross-sectional study, 32,438 males (49.0 +/- 11.9 years old) and 31,009 females (48.2 +/- 11.6 years old) receiving a health checkup from 2000 to 2005 were included. Longitudinally, 5,444 males (49.8 +/- 10.7 years old) and 4,980 females (50.4 +/- 9.3 years old) participating in both 2000 and 2005 were included. Multiple logistic regression analyses were performed for both sexes, adjusted for age, BMI, and smoking. The prevalence of fatty liver in non-, occasional, daily moderate, and daily heavy drinkers was 28.5, 27.5, 18.7, and 19.1% in men and 12.4, 7.7, 5.4, and 6.7% in women, respectively (inverse association, P < or = 0.05 for both). Occasional, daily moderate, and daily heavy drinking in men and occasional and daily moderate drinking in women were inversely associated with fatty liver in the cross-sectional study. Daily moderate and heavy drinking appeared protective in men in the longitudinal study. Alcohol drinking may not be a major risk for fatty liver in Japanese undergoing a health checkup.
- Subjects
JAPAN; PHYSIOLOGICAL effects of alcohol; FATTY liver; MEDICAL screening; ULTRASONIC imaging; MULTIVARIATE analysis; REGRESSION analysis; DISEASE risk factors; BLOOD sugar analysis; BODY weight; ALCOHOL drinking; BODY mass index; DIAGNOSIS
- Publication
Digestive Diseases & Sciences, 2010, Vol 55, Issue 1, p176
- ISSN
0163-2116
- Publication type
journal article
- DOI
10.1007/s10620-008-0693-0