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- Title
Letter to the Editor: Glycemic Index/Load Effect on Amyotrophic Lateral Sclerosis Progression: Potential Interaction with Riluzole.
- Authors
Brooks, Benjamin Rix
- Abstract
This article, titled "Letter to the Editor: Glycemic Index/Load Effect on Amyotrophic Lateral Sclerosis Progression: Potential Interaction with Riluzole," discusses the ALS COSMOS Study Group's research on the impact of baseline glycemic index/load on the rate of ALS progression. The study aims to inform the development of clinical trials for evaluating treatments in short-term phases. The researchers also explore the potential interaction between riluzole, a medication used to treat ALS, and glucose metabolism. The article raises questions about the proportion of ALS patients using riluzole and the distribution of patients across different glycemic index/load quartiles. The Food and Drug Administration recommends assessing treatments separately and together to determine their effects. Further research is needed to clarify these findings.
- Subjects
AMYOTROPHIC lateral sclerosis; GLYCEMIC index; RILUZOLE
- Publication
Annals of Neurology, 2024, Vol 96, Issue 1, p208
- ISSN
0364-5134
- Publication type
Article
- DOI
10.1002/ana.26970