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- Title
Serum cholesterol level comparison: control subjects, anxiety disorder patients, and obsessive-compulsive disorder patients.
- Authors
Peter, Helmut; Hand, Iver; Hohagen, Fritz; Koenig, Anne; Mindermann, Olaf; Oeder, Frank; Wittich, Markus
- Abstract
<bold>Objective: </bold>To determine whether panic disorder is associated with elevated serum cholesterol levels. Serum cholesterol levels of panic disorder patients are reported to be elevated. This could explain the higher-than-expected cardiovascular mortality in this population. Some evidence exists wherein cholesterol levels are also increased in patients with general anxiety disorder and phobias. To date, there are only 2 reports on cholesterol levels of obsessive-compulsive disorder (OCD) patients, giving controversial results.<bold>Method: </bold>We compared serum cholesterol levels of anxiety disorder patients, OCD patients, and normal control subjects with each other (n = 60 in each group). Serum cholesterol was measured in each subject before treatment. Subjects of the 3 groups were matched by age and sex.<bold>Results: </bold>Patients with anxiety disorders and OCD had elevated cholesterol levels, compared with normal control subjects. Cholesterol levels in OCD patients were comparable with those in patients with phobia.<bold>Conclusions: </bold>Our data support the assumption that elevation in cholesterol level is not a specific feature of panic disorder (as most assumed), but more generally associated with anxiety disorders. Increased cholesterol levels in patients with anxiety disorders and OCD may be of clinical relevance.
- Subjects
PANIC disorders; BLOOD cholesterol; AMINES; SEROTONIN uptake inhibitors; AGORAPHOBIA; CHOLESTEROL; COMPARATIVE studies; RESEARCH methodology; MEDICAL cooperation; OBSESSIVE-compulsive disorder; RESEARCH; EVALUATION research; ANXIETY disorders; THERAPEUTICS
- Publication
Canadian Journal of Psychiatry, 2002, Vol 47, Issue 6, p557
- ISSN
0706-7437
- Publication type
journal article
- DOI
10.1177/070674370204700608