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- Title
Cytogenetic abnormalities in 179 cases with male infertility in Western Region of Turkey: Report and review.
- Authors
Akgul, M.; Ozkinay, F.; Ercal, D.; Cogulu, O.; Dogan, O.; Altay, B.; Tavmergen, E.; Gunduz, C.; Ozkinay, C.
- Abstract
Purpose In this study we aimed to evaluate the postnatally screened karyotype results in couples who were referred because of primary infertility between 2000 and 2006 in Izmir. Methods The records of a total of 179 cases were evaluated retrospectively. Results A total of 21 cases (11.74%) showed chromosomal alteration. Thirteen (7.26%) were 47,XXY; three (1.68%) were pericentric inversion of chromosome 9; one (0.56%) 46,XY/45,XO; one (0.56%) 46,XY/47,XXY/48,XXXY; one (0.56%) 46,XY,t(X;1); one (0.56%) 46,XY/46,XY,del (Y)(q11.2) and one (0.56%) 46,XX. Conclusions The rate of gonosomal chromosomal abnormalities was nearly three times higher in our region than the rate in the literature. Chromosomal analysis is strongly suggested particularly in those who suffer fertility problems.
- Subjects
TURKEY; MALE infertility; INFERTILITY; HUMAN abnormalities; HUMAN cytogenetics; KARYOTYPES
- Publication
Journal of Assisted Reproduction & Genetics, 2009, Vol 26, Issue 2/3, p119
- ISSN
1058-0468
- Publication type
Article
- DOI
10.1007/s10815-009-9296-8