We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Installing Reduction Responsiveness into Biomolecules by Introducing Nitroaryl Groups.
- Authors
Higashi, Sayuri L.; Shintani, Yuki; Ikeda, Masato
- Abstract
Artificially synthesized stimuli‐responsive biomolecules are attractive as molecular tools for monitoring and modulating biological systems. In biological systems, redox stimuli are common, and their dysregulation is typically linked to various abnormal or disease states. In this Concept article, the molecular design of reduction‐responsive biomolecules, such as peptides, nucleic acids, and saccharides, which are produced by introducing nitroaryl groups into them, is reviewed with a special emphasis on simple 4‐nitrobenzene‐based motifs.
- Subjects
BIOMOLECULES; BIOLOGICAL monitoring; BIOLOGICAL systems; DISEASE progression; SACCHARIDES
- Publication
Chemistry - A European Journal, 2022, Vol 28, Issue 48, p1
- ISSN
0947-6539
- Publication type
Article
- DOI
10.1002/chem.202201103