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- Title
Methyl Pothoscandensate, a New ent-18(4→3)-Abeokaurane from Pothos scandens.
- Authors
Liu, Hong-Xin; Bi, Jun-Long; Wang, Yue-Hu; Gu, Wei; Su, Yao; Liu, Fang; Yang, Shi-Xian; Hu, Guang-Wan; Luo, Ji-Feng; Yin, Ge-Fen; Long, Chun-Lin
- Abstract
Methyl pothoscandensate ( 1), a new molecular skeleton of ent-18(4→3)-abeokaurane, along with eight known compounds was isolated from the whole plant of Pothos scandens. The structure of the new compound was established by spectroscopic techniques and confirmed by single-crystal X-ray diffraction. The inhibitory activity of selected compounds against porcine respiratory and reproductive syndrome virus (PRRSV) was measured by the cytopathic effect (CPE) method. Compound 1 showed weak effect on PRRSV with an IC50 value of 40.3±8.3 μ M ( TI=15.7).
- Subjects
URETHANE; SINGLE crystals; X-ray diffraction; SPECTRUM analysis; COMPLEX compounds
- Publication
Helvetica Chimica Acta, 2012, Vol 95, Issue 7, p1231
- ISSN
0018-019X
- Publication type
Article
- DOI
10.1002/hlca.201200006