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- Title
Effect of vitamin D supplementation in the institutionalized elderly.
- Authors
Himeno, Masako; Tsugawa, Naoko; Kuwabara, Akiko; Fujii, Minori; Kawai, Nobuko; Kato, Yuzuru; Kihara, Noriko; Toyoda, Tomoko; Kishimoto, Masami; Ogawa, Yoko; Kido, Shoko; Noike, Toshiaki; Okano, Toshio; Tanaka, Kiyoshi
- Abstract
An intervention study with vitamin D supplementation was conducted in order to study the amount of vitamin D required in the elderly. Sixty-four institutionalized elderly were randomly assigned to two groups: group (A) to take a beverage containing 200 mg calcium daily, and group (B) to take a beverage containing 200 mg calcium and 5 microg vitamin D daily for 30 days. Prior to the study, the subjects' average vitamin D intake was 7.3 microg/day, which is approximately 150% of the current adequate intake (AI), however their mean plasma 25 OH-D level at baseline was only 12 ng/mL, strongly indicating hypovitaminosis D. During the study, average plasma 25 OH-D concentration significantly increased to 14.7 ng/mL in group (B), but not in group (A). However, group (B) was still in the hypovitaminosis range. Thus, daily intake exceeding the current AI of 5 microg is required for the institutionalized elderly.
- Subjects
CALCIUM; THERAPEUTIC use of vitamin D; VITAMIN therapy; BLOOD testing; NUTRITION disorders; COMPARATIVE studies; DIETARY supplements; RESEARCH methodology; MEDICAL cooperation; NURSING care facilities; NUTRITION; PARATHYROID hormone; RESEARCH; TIME; VITAMIN D; EVALUATION research; RANDOMIZED controlled trials; DIAGNOSIS; THERAPEUTICS
- Publication
Journal of Bone & Mineral Metabolism, 2009, Vol 27, Issue 6, p733
- ISSN
0914-8779
- Publication type
journal article
- DOI
10.1007/s00774-009-0081-7