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- Title
Improved correction formulas to estimate iohexol clearance from simple models.
- Authors
Dong, Qian; Fuhr, Uwe; Schaeffner, Elke; van der Giet, Markus; Ebert, Natalie; Taubert, Max
- Abstract
The article discusses research which demonstrated that a three-compartment pharmacokinetic model provides better iohexol clearance estimates than the two-compartment approach in measuring glomerular filtration rate in elderly subjects. Topics include the complicated implementation of the presented model in clinical and research practice, the required technical expertise to address the challenges, and a viable alternative to the complex Bayesian software.
- Subjects
GERMANY; GLOMERULAR filtration rate; MEDICAL quality control; PREDICTIVE tests; CONTRAST media; DRUG design; PROFESSIONAL competence; RESEARCH funding; MEDICAL prescriptions; OLD age
- Publication
European Journal of Clinical Pharmacology, 2023, Vol 79, Issue 9, p1215
- ISSN
0031-6970
- Publication type
Article
- DOI
10.1007/s00228-023-03535-y