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- Title
Anaemia of renal disease: pathophysiology and treatment updates.
- Authors
Chalhoub, Serge; Langston, Cathy
- Abstract
Chronic kidney disease (CKD) often leads to renal anaemia, due to gradual reduction of erythropoietin-producing renal cells. About 15-30% of geriatric cats develop CKD, with renal disease being the primary cause of death of older cats. Of those cats with CKD, up to 65% in later-stage CKD will develop renal anaemia. Recognising and treating anaemia of renal disease is an important part of CKD therapy in both dogs and cats. The use of erythropoiesis-stimulating agents (ESAs) is standard-of-care in humans and becoming more used in veterinary medicine. Darbepoetin alfa (DA) has been shown to be effective in the treatment of renal anaemia.
- Subjects
KIDNEY diseases in animals; RENAL anemia; DARBEPOETIN alfa; ERYTHROPOIESIS; TREATMENT of cat diseases; EPOETIN alfa (Drug); PATHOLOGICAL physiology; THERAPEUTICS
- Publication
UK-Vet Companion Animal, 2015, Vol 20, Issue 8, p448
- ISSN
2053-0889
- Publication type
Article
- DOI
10.12968/coan.2015.20.8.448