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- Title
Association of Serum Anti-Heat Shock Protein 27 Antibody with Obesity Risk among Healthy Individuals in MASHAD Study.
- Authors
Sadabadi, Fatemeh; Asadi, Zahra; Heidari-Bakavoli, Alireza; Daroudi, Susan; Saberi-Karimian, Maryam; Saljoughian, Saniya; Shahi, Maryam; Safarian, Mohammad; Nematy, Mohsen; Fern, Gordon; Mobarhan, Majid Ghayour; Mouhebati, Mohsen
- Abstract
Introduction: The association between the serum antibody titer of several heat shock proteins (HSPs) and cardiovascular disease (CVD) risk factors so far has been the subject of several previous studies. Aim: To evaluate the association of adiposity indices and HSP-27 antibody titers in healthy individuals. Materials and Methods: Overall 4823 individuals were recruited from Mashhad Stroke and Heart Atherosclerotic Disorders Study (MASHAD study), that included 1496 individuals with normal-weight (body mass index (BMI) <25 kg/m2), 1975 individuals with over-weight (BMI 25-30 kg/m2), and 1352 individuals with obesity (BMI≥ 30 kg/m2). Results: The serum anti-HSP-27 antibody titers were not significantly different among obese individuals [0.21 (0.11 - 0.34) absorbency unit (AU)], over-weight individuals [0.19 (0.10 - 0.33) AU] and normal-weight individuals [0.19 (0.10 - 0.33) AU]. Conclusions: we have found no significant relationship among anti-HSP-27 antibody concentration and degrees of adiposity among Iranian adults.
- Subjects
HEAT shock proteins; ANTIBODY titer; IRANIANS; BODY mass index; OBESITY
- Publication
Journal of Cardio-Thoracic Medicine, 2022, Vol 10, Issue 3, p1010
- ISSN
2345-2447
- Publication type
Article