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- Title
The reduction in fitness from genetic drift at heterotic loci in small populations.
- Authors
Robertson, Alan
- Abstract
In finite populations, loci maintained segregating by hétérozygote superiority will be disturbed from their equilibrium positions by genetic sampling and the mean fitness of individuals will consequently be reduced. A general expression for this reduction is obtained for the segregation of two alleles. If the probability of continued segregation at the locus is high, the reduction tends to 1/4N, irrespective of the strength of selection, where N is the effective population size. This will always be much less than the segregation load. If n alleles are segregating, so that all heterozygotes have the same fitness, the reduction tends to (n−1)/4N.
- Publication
Genetics Research, 1970, Vol 15, Issue 2, p257
- ISSN
0016-6723
- Publication type
Article
- DOI
10.1017/S0016672300001580