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- Title
Males and females with first episode psychosis present distinct profiles of social cognition and metacognition.
- Authors
Ferrer-Quintero, M.; Fernández, D.; López-Carrilero, R.; Birulés, I.; Barajas, A.; Lorente-Rovira, E.; Luengo, A.; Díaz-Cutraro, L.; Verdaguer, M.; García-Mieres, H.; Gutiérrez-Zotes, A.; Grasa, E.; Pousa, E.; Huerta-Ramos, E.; Pélaez, T.; Barrigón, M. L.; Gómez-Benito, J.; González-Higueras, F.; Ruiz-Delgado, I.; Cid, J.
- Abstract
Deficits in social cognition and metacognition impact the course of psychosis. Sex differences in social cognition and metacognition could explain heterogeneity in psychosis. 174 (58 females) patients with first-episode psychosis completed a clinical, neuropsychological, social cognitive, and metacognitive assessment. Subsequent latent profile analysis split by sex yielded two clusters common to both sexes (a Homogeneous group, 53% and 79.3%, and an Indecisive group, 18.3% and 8.6% of males and females, respectively), a specific male profile characterized by presenting jumping to conclusions (28.7%) and a specific female profile characterized by cognitive biases (12.1%). Males and females in the homogeneous profile seem to have a more benign course of illness. Males with jumping to conclusions had more clinical symptoms and more neuropsychological deficits. Females with cognitive biases were younger and had lower self-esteem. These results suggest that males and females may benefit from specific targeted treatment and highlights the need to consider sex when planning interventions.
- Subjects
SOCIAL perception; METACOGNITION; PSYCHOSES; FEMALES; MALES
- Publication
European Archives of Psychiatry & Clinical Neuroscience, 2022, Vol 272, Issue 7, p1169
- ISSN
0940-1334
- Publication type
Article
- DOI
10.1007/s00406-022-01438-0