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- Title
Increased basement membrane turnover and strongly attenuated interstitial matrix turnover is a key pathological feature of haemophilia.
- Authors
Manon‐Jensen, T.; Hua, B. L.; Olsen, E. H. N.; Sun, S.; Gudme, C. N.; Li, J.; Lei, W.; Vandahl, B.; Roepstorff, K.; Kjelgaard‐Hansen, M.; Zhao, Y.; Karsdal, M. A.
- Abstract
The article discusses central pathological feature of many diseases in altered extracellular matrix. It also discusses current investigation in haemophilia, cause of recurrent and prolonged bleeding of the basement membranes and the interstitial matrix, collagen biomarkers of basement membrane and interstitial matrix turnover in a well-characterized case-control study.
- Subjects
EXTRACELLULAR matrix; INTERPHOTORECEPTOR matrix; METALLOPROTEINASES; ENDOTHELIAL cells; GLYCOPROTEINS
- Publication
Haemophilia, 2017, Vol 23, Issue 6, pe515
- ISSN
1351-8216
- Publication type
Article
- DOI
10.1111/hae.13329