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- Title
National Trends in the Distribution of Candida Species Causing Candidemia in Japan from 2003 to 2014:A Report by the Epidemiological Investigation Committee for Human Mycoses in Japan.
- Authors
Hiroshi Kakeya; Koichi Yamada; Yukihiro Kaneko; Katsunori Yanagihara; Kazuhiro Tateda; Shigefumi Maesaki; Yoshio Takesue; Kazunori Tomono; Jun-ichi Kadota; Mitsuo Kaku; Yoshitsugu Miyazaki; Katsuhiko Kamei; Kazutoshi Shibuya; Yoshitiho Niki; Minoru Yoshida; Yoshihiro Sei
- Abstract
The Epidemiological Investigation Committee for Human Mycoses in Japan performed a retrospective epidemiological survey of candidemia and causative Candida species. Data from 2003 to 2014 were collected from 10 Japanese university hospitals. A total of 328,318 blood cultures were included. The prevalence of fungi in all cultures and in positive cultures were 0.58 ± 0.09% and 4.46 ± 0.66%, respectively. Among the results that were positive for Candida species (N = 1,921), Candida albicans was the most common species (39.5%) and was followed by Candida parapsilosis (23.3%), Candida glabrata (13.2%), Candida tropicalis (7.1%), Candida krusei (3.2%), and others (13.7%). During the last 6 years, the frequency of C. albicans has significantly decreased in Japan, while that of C. glabrata has increased. Additional surveys are needed to continuously monitor the trends in the distribution of candidemia.
- Subjects
JAPAN; CANDIDIASIS treatment; INVASIVE candidiasis; CANDIDEMIA; COMMUNICABLE disease treatment; MYCOSES; PUBLIC health; THERAPEUTICS
- Publication
Medical Mycology Journal, 2018, Vol 59, Issue 1, pE19
- ISSN
2185-6486
- Publication type
Article
- DOI
10.3314/mmj.17-00014