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- Title
Study of DNA-methylation patterns at chromosome 15q11-q13 in children born after ICSI reveals no imprinting defects.
- Authors
Manning, Martina; Lissens, Willy
- Abstract
Examines DNA-methylation patterns at chromosome 15q11-q13 in children born after intracytoplasmic sperm injection (ICSI). Association of imprinting defects in the region with neurogenetic disorders; Detection of a regular DNA-methylation pattern in the Prader-Willi syndrome/Angelman syndrome region; Absence of a higher risk of DNA-methylation defects for children born after ICSI.
- Subjects
DNA; CHROMOSOME abnormalities; GENOMIC imprinting; PRADER-Willi syndrome; ANGELMAN syndrome; METHYLATION
- Publication
Molecular Human Reproduction, 2000, Vol 6, Issue 11
- ISSN
1360-9947
- Publication type
Article
- DOI
10.1093/molehr/6.11.1049